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Article

Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling

Alpha-lipoic acid (α-LA), a well-known antioxidant, was proved to active ALDH2 in nitrate tolerance and diabetic animal model. However, the therapeutic advantage of α-LA for heart failure and related signaling...

Wenjia Li, Lei Yin, **aolei Sun, Jian Wu, Zhen Dong, Kai Hu… in Cell Death & Disease (2020)