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  1. No Access

    Article

    SUMOylation of RNF146 results in Axin degradation and activation of Wnt/β-catenin signaling to promote the progression of hepatocellular carcinoma

    Aberrant SUMOylation contributes to the progression of hepatocellular carcinoma (HCC), yet the molecular mechanisms have not been well elucidated. RING-type E3 ubiquitin ligase RNF146 is a key regulator of the...

    Wenjia Li, Qingfang Han, Yuanxin Zhu, Yingshi Zhou, **gyuan Zhang, Weijun Wu… in Oncogene (2023)

  2. Article

    Open Access

    NR1B2 suppress kidney renal clear cell carcinoma (KIRC) progression by regulation of LATS 1/2-YAP signaling

    Kidney Renal Clear Cell Carcinoma (KIRC) accounts for 75% of all renal cancers. Previous study had conflict evidences regarding NR1B2 role in cancer, and its expression and biological role in KIRC remained unc...

    Lei Yin, Wenjia Li, Guangchun Wang, Heng Shi… in Journal of Experimental & Clinical Cancer … (2019)

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