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    Article

    C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport

    Sterol regulatory element binding transcription factors (SREBPs) play a crucial role in lipid homeostasis. They are processed and transported to the nucleus via COPII, where they induce the expression of lipog...

    Yachen Wu, Wenzhong Zheng, Guofeng Xu, Lijun Zhu in Cell Death & Differentiation (2024)

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    Open Access

    Multi-omics analysis of tumor angiogenesis characteristics and potential epigenetic regulation mechanisms in renal clear cell carcinoma

    Tumor angiogenesis, an essential process for cancer proliferation and metastasis, has a critical role in prognostic of kidney renal clear cell carcinoma (KIRC), as well as a target in guiding treatment with an...

    Wenzhong Zheng, Shiqiang Zhang, Huan Guo, **aobao Chen in Cell Communication and Signaling (2021)

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    Article

    HO-1 Overexpressed Mesenchymal Stem Cells Ameliorate Sepsis-Associated Acute Kidney Injury by Activating JAK/stat3 Pathway

    Stem cell therapy has been increasingly used in the treatment of sepsis-associated acute kidney injury (AKI). Engineering stem cells, through genetic method, for optimized therapeutic outcome is a desirable st...

    Xuetao Yan, **aoli Cheng, **anghu He in Cellular and Molecular Bioengineering (2018)