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  1. Article

    Open Access

    MANF ameliorates DSS-induced mouse colitis via restricting Ly6ChiCX3CR1int macrophage transformation and suppressing CHOP-BATF2 signaling pathway

    Mesencephalic astrocyte-derived neurotrophic factor (MANF), an endoplasmic reticulum stress-inducible secreting protein, has evolutionarily conserved immune-regulatory function that contributes to the negative...

    Lin Yang, Wen-wen Shen, Wei Shao, Qing Zhao, Gao-zong Pang… in Acta Pharmacologica Sinica (2023)

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  2. Article

    Open Access

    The relationship between obesity and diabetic nephropathy in China

    The epidemic of diabetic nephropathy (DN) has been paralleled by rapid increases in both obesity and diabetes in China. The aim of this study was to investigate the natural history of DN and the association of...

    Hui-Mei Chen, Wen-Wen Shen, Yong-Chun Ge, Yi-De Zhang, Hong-Lang **e… in BMC Nephrology (2013)

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  3. Article

    Open Access

    Homo-binding character of LMO2 isoforms and their both synergic and antagonistic functions in regulating hematopoietic-related target genes

    The human lmo2 gene plays important roles in hematopoiesis and is associated with acute T lymphocyte leukemia. The gene encodes two protein isoforms, a longer form LMO2-L and a shorter form LMO2-S. Both isoforms ...

    Wei Sun, Wen-Wen Shen, Shuang Yang, Fen Hu, Yang Gao… in Journal of Biomedical Science (2010)

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