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  1. Article

    Open Access

    MANF ameliorates DSS-induced mouse colitis via restricting Ly6ChiCX3CR1int macrophage transformation and suppressing CHOP-BATF2 signaling pathway

    Mesencephalic astrocyte-derived neurotrophic factor (MANF), an endoplasmic reticulum stress-inducible secreting protein, has evolutionarily conserved immune-regulatory function that contributes to the negative...

    Lin Yang, Wen-wen Shen, Wei Shao, Qing Zhao, Gao-zong Pang… in Acta Pharmacologica Sinica (2023)

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  2. Article

    Open Access

    Homo-binding character of LMO2 isoforms and their both synergic and antagonistic functions in regulating hematopoietic-related target genes

    The human lmo2 gene plays important roles in hematopoiesis and is associated with acute T lymphocyte leukemia. The gene encodes two protein isoforms, a longer form LMO2-L and a shorter form LMO2-S. Both isoforms ...

    Wei Sun, Wen-Wen Shen, Shuang Yang, Fen Hu, Yang Gao… in Journal of Biomedical Science (2010)

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