1,146 Result(s)
within
Wen-** Zeng
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Article
Atypical phenotypes and novel OCRL variations in southern Chinese patients with Lowe syndrome
Lowe syndrome is characterized by the presence of congenital cataracts, psychomotor retardation, and dysfunctional proximal renal tubules. This study presents a case of an atypical phenotype, investigates the ...
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Open AccessAsymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSA
The development of new antibiotics continues to pose challenges, particularly considering the growing threat of multidrug-resistant Staphylococcus aureus. Structurally diverse natural products provide a promising...
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Cross-linked Sodium Hyaluronate Gel with PLLA-b-PEG Microsphere for Facial Contouring in Chinese: A Retrospective Study
In Asia, the demand for cosmetic facial treatments has surged due to technological advancements, increased social acceptability, and affordability. Poly-l-lactic acid (PLLA) fillers, known for their biocompatibil...
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Achieving strength–ductility synergy in novel paramagnetic Fe-based medium-entropy alloys through deep cryogenic deformation
Cryogenic pre-deformation treatment has been widely used to effectively improve the comprehensive mechanical properties of steels and novel metals. However, the dislocation evolution and phase transformation i...
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Tensor Robust Principal Component Analysis via Non-convex Low-Rank Approximation Based on the Laplace Function
Recently, the tensor robust principal component analysis (TRPCA), aiming to recover the true low-rank tensor from noisy data, has attracted considerable attention. In this paper, we solve the TRPCA problem und...
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Overexpression of the MiAGL1 gene from mango promoted flowering in transgenic Arabidopsis
MADS-box genes play a vital role in the vegetative and reproductive growth of plants. In this study, a MiAGL1 gene was cloned and identified from mango (Mangifera indica L.). The DNA sequence of AGAMOUS-LIKE1 (Mi...
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Open AccessLow friction under ultrahigh contact pressure enabled by self-assembled fluorinated azobenzene layers
Extensive efforts have been made to pursue a low-friction state with promising applications in many fields, such as mechanical and biomedical engineering. Among which, the load capacity of the low-friction sta...
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Coupling N-do** and confined Co3O4 on carbon nanotubes by polydopamine coating strategy for pleiotropic water purification
The development of effective and sustainable solutions for pleiotropic water purification becomes urgent and attractive. Heterogeneous Fenton-like catalysts for activation of peroxymonosulfate (PMS) to purify ...
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Open AccessA pan-KRAS degrader for the treatment of KRAS-mutant cancers
KRAS mutations are highly prevalent in a wide range of lethal cancers, and these mutant forms of KRAS play a crucial role in driving cancer progression and conferring resistance to treatment. While there have bee...
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Open AccessNicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying mechanism of nicotinate-curcumin (NC) in the treatment of NASH remain unce...
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Pressure-driven metallization with significant changes of structural and photoelectric properties in two-dimensional EuSbTe3
Two-dimensional materials are widely considered to be highly promising for the development of photodetectors. To improve the performance of these devices, researchers often employ techniques such as defect eng...
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Inflammation-Responsive Mesoporous Silica Nanoparticles with Synergistic Anti-inflammatory and Joint Protection Effects for Rheumatoid Arthritis Treatment
Joint destruction is a major burden and an unsolved problem in rheumatoid arthritis (RA) patients. We designed an intra-articular mesoporous silica nanosystem (MSN-TP@PDA-GlcN) with anti-inflammatory and joint...
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Open AccessA cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection
Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies. Considering the complex life cycle of EBV, develo** vaccines targeting key entry glycop...
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Open AccessInfluence of ABC stroke score on late recurrence of paroxysmal atrial fibrillation following radiofrequency catheter ablation
In this study we investigated the impact of ABC stroke score on the recurrence of paroxysmal atrial fibrillation (PAF) following radiofrequency catheter ablation (RFCA).
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Open AccessDNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is characterised by persistent airway inflammation even after cigarette smoking cessation. Neutrophil extracellular traps (NETs) have been implicated in COPD severi...
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Characteristics of tandem repeat inheritance and sympathetic nerve involvement in GAA-FGF14 ataxia
Intronic GAA repeat expansion ([GAA] ≥250) in FGF14 is associated with the late-onset neurodegenerative disorder, spinocerebellar ataxia 27B (SCA27B, GAA-FGF14 ataxia). We aim to determine the prevalence of the G...
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Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Open AccessMolecular docking and MD simulation studies of 4-thiazol-N-(pyridin-2-yl)pyrimidin-2-amine derivatives as novel inhibitors targeted to CDK2/4/6
Nowadays, cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have been approved for treating metastatic breast cancer and have achieved inspiring curative effects. But some discoveries have indicated that CDK 4/6...
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Open AccessEffects of emulsifiers on lipid metabolism and performance of yellow-feathered broilers
Reducing production costs while producing high-quality livestock and poultry products is an ongoing concern in the livestock industry. The addition of oil to livestock and poultry diets can enhance feed palata...
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Open AccessNitrogen addition has divergent effects on phosphorus fractions in four types of soils
Globally increasing atmospheric nitrogen (N) deposition has altered soil phosphorus (P) transformations and availability, and thereby influenced structure and function of terrestrial ecosystems. Edaphic charac...
