10 Result(s)
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Article
Open AccessDynamic changes in protein interaction between AKAP95 and Cx43 during cell cycle progression of A549 cells
Here we show that A-kinase anchoring protein 95 (AKAP95) and connexin 43 (Cx43) dynamically interact during cell cycle progression of lung cancer A549 cells. Interaction between AKAP95 and Cx43 at different ce...
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Open AccessCCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability
Leber congenital amaurosis (LCA) is a hereditary early-onset retinal dystrophy that is accompanied by severe macular degeneration. In this study, novel compound heterozygous mutations were identified as LCA-ca...
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Open AccessPrognosis and value of preoperative radiotherapy in locally advanced rectal signet-ring cell carcinoma
As well known, signet-ring cell carcinoma (SRCC) is a rare histological subtype of colorectal adenocarcinoma, which has been associated with poor prognosis and resistant to non-surgery therapy compared with co...
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Article
Open AccessATP-dependent modulation of MgtE in Mg2+ homeostasis
Magnesium is an essential ion for numerous physiological processes. MgtE is a Mg2+ selective channel involved in the maintenance of intracellular Mg2+ homeostasis, whose gating is regulated by intracellular Mg2+ ...
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Article
Open AccessAdjuvant imatinib for patients with high-risk gastrointestinal stromal tumors: a retrospective cohort study
The duration of adjuvant imatinib for high-risk patients with gastrointestinal stromal tumors (GISTs) is still controversial. Therefore, we retrospectively analyzed the data of high-risk patients with GISTs to...
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Open AccessCrustal movement and strain distribution in East Asia revealed by GPS observations
East Asia is bounded by the Indian plate to the southwest and the Pacific and Philippine plates to the east, and has undergone complex tectonic evolution since ~55 Ma. In this study, we collect and process thr...
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Open AccessComparative Clinicopathologic Characteristics and Outcomes of Paediatric and Adult Xp11 Translocation Renal Cell Carcinomas: a Retrospective Multicentre Study in China
This study aimed to compare the clinicopathologic features and prognosis in patients with Xp11 translocation renal cell carcinomas (RCCs). In total, 8083 RCCs were screened at five centres from January 2007 to...
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Open AccessFermi-arc supercurrent oscillations in Dirac semimetal Josephson junctions
One prominent hallmark of topological semimetals is the existence of unusual topological surface states known as Fermi arcs. Nevertheless, the Fermi-arc superconductivity remains elusive. Here, we report the c...
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Open AccessThe suitability of NONO-TFE3 dual-fusion FISH assay as a diagnostic tool for NONO-TFE3 renal cell carcinoma
NONO-TFE3 RCC is a subtype of Xp11.2 translocation renal cell carcinoma (RCC). So far, only a small amount of NONO-TFE3 RCC have been reported owing to lack of effective diagnosis methods. Utilizing the novel dua...
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Article
Open AccessInhibitory effects of Schisandrin C on collagen behavior in pulmonary fibrosis
Pulmonary fibrosis (PF) is a serious progressive fibrotic disease that is characterized by excessive accumulation of extracellular matrix (ECM), thus resulting in stiff lung tissues. Lysyl oxidase (LOX) is an ...
