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Article
Open AccessCCL11/CCR3-dependent eosinophilia alleviates malignant pleural effusions and improves prognosis
Malignant pleural effusion (MPE) is a common occurrence in advanced cancer and is often linked with a poor prognosis. Eosinophils were reported to involve in the development of MPE. However, the role of eosino...
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Article
Open AccessTriglyceride Glucose Index for the Detection of Diabetic Kidney Disease and Diabetic Peripheral Neuropathy in Hospitalized Patients with Type 2 Diabetes
The triglyceride–glucose index (TyG) has been identified as a dependable and simple indicator marker of insulin resistance (IR). Research has demonstrated a correlation between macrovascular complications and ...
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Article
Open AccessEarly changes in cardiac troponin T and NT-proBNP levels in neonates receiving ECMO support: a single-center experience
This study aimed to examine the changes in absolute value and decline rate of early serum cardiac troponin T (cTnT) and N-terminal pro b-type natriuretic peptide (NT-proBNP) in neonates who received veno-arter...
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Article
Open AccessClinical characteristics of obese, fixed airway obstruction, exacerbation-prone phenotype and comorbidities among severe asthma patients: a single-center study
Severe asthma places a large burden on patients and society. The characteristics of patients with severe asthma in the Chinese population remain unclear.
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Article
Open AccessHigher plasma aldosterone concentrations in patients with aortic diseases and hypertension: a retrospective observational study
Aortic diseases remain a highly perilous macrovascular condition. The relationship between circulating aldosterone and aortic diseases is rarely explored, thus we investigated the difference in plasma aldoster...
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Article
Open AccessAssociation of hyperuricemia combined with sarcopenia on ASCVD risk
Hyperuricemia and sarcopenia are both strongly linked to an increased risk of atherosclerotic cardiovascular disease (ASCVD), and this study was designed to look into the interactive effects of hyperuricemia o...
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Article
Correction to: MiR-139 Affects Radioresistance in Esophageal Cancer by Targeting the PDK1/AKT/Cyclin D1 Signaling Pathway
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Article
Open AccessRisk factors for prolonged preoperative waiting time of intertrochanteric fracture patients undergoing operative treatment
Intertrochanteric fracture is a common fracture in older adults. We observed the case characteristics of intertrochanteric fracture and analyzed the risk factors for prolonged preoperative waiting time based o...
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Article
Open AccessComputed tomography features and clinicopathological characteristics of gastric glomus tumor
Gastric glomus tumor (GGT) is a rare neoplasm that is difficult to distinguish from other gastric submucosal tumors due to a lack of diagnostic experience. The goal of this study was to better understand GGT b...
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Article
Open AccessConstruction of genetic classification model for coronary atherosclerosis heart disease using three machine learning methods
Although the diagnostic method for coronary atherosclerosis heart disease (CAD) is constantly innovated, CAD in the early stage is still missed diagnosis for the absence of any symptoms. The gene expression le...
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Article
Open AccessMechanical power normalized to predicted body weight is associated with mortality in critically ill patients: a cohort study
Mechanical power (MP), defined as the amount of energy produced by mechanical ventilation and released into the respiratory system, was reportedly a determining factor in the pathogenesis of ventilator-induced...
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Article
Open AccessClinical characteristics of patients with chronic cough in Guangdong, China: a multicenter descriptive study
The clinical characteristics of patients with chronic cough are reported only in single-center survey in China, being significantly different from that in western countries. Here, we performed a multicenter st...
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Article
Open AccessMetagenomic Next-Generation Sequencing for the Diagnosis of Pneumocystis jirovecii Pneumonia in Non-HIV-Infected Patients: A Retrospective Study
This study aimed to evaluate the utility of metagenomic next-generation sequencing (mNGS) for the diagnosis of Pneumocystis jirovecii pneumonia (PJP) in non-human immunodeficiency virus-infected patients.
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Article
Open AccessIdentification of biomarkers associated with metabolic cardiovascular disease using mRNA-SNP-miRNA regulatory network analysis
CVD is the leading cause of death in T2DM patients. However, few biomarkers have been identified to detect and diagnose CVD in the early stage of T2DM. The aim of our study was to identify the important mRNAs,...
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Article
Open AccessCorrection to: Pharmacodynamics of efavirenz 400 mg in treatment-naïve Chinese HIV-infected patients in a prospective cohort study
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessPharmacodynamics of efavirenz 400 mg in treatment-naïve Chinese HIV-infected patients in a prospective cohort study
The plasma concentration of patients treated with efavirenz (EFV) 600 mg was found to exceed the upper limit of the proposed therapeutic window in most Chinese HIV-infected individuals; thus, dosage reduction ...
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Article
Open AccessThe effect of glucocorticoids on serum cystatin C in identifying acute kidney injury: a propensity-matched cohort study
Glucocorticoids may impact the accuracy of serum cystatin C (sCysC) in reflecting renal function. We aimed to assess the effect of glucocorticoids on the performance of sCysC in detecting acute kidney injury (...
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Article
Open AccessTargeting cancer stem cell pathways for cancer therapy
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been considered promising therapeutic targets for cancer therapy. These cells have self-renewal capacity and differentiation ...
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Article
Open AccessCase report: life-threatening coronary artery spasm under transversus abdominis plane block in combination with general anesthesia
Many cases of coronary artery spasm (CAS) during general plus epidural anesthesia have been reported. But transversus abdominis plane(TAP) block in combination with general anesthesia has not been reported to ...
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Article
Open AccessIdentification of high-risk plaque features in intracranial atherosclerosis: initial experience using a radiomic approach
To evaluate a quantitative radiomic approach based on high-resolution magnetic resonance imaging (HR-MRI) to differentiate acute/sub-acute symptomatic basilar artery plaque from asymptomatic plaque.