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  1. Article

    Open Access

    Activation of PPAR-α attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis and mitochondrial injury via upregulating 14-3-3η

    This study aimed to explore the effects of peroxisome proliferator-activated receptor α (PPAR-α), a known inhibitor of ferroptosis, in Myocardial ischemia/reperfusion injury (MIRI) and its related mechanisms. ...

    Tie Hu, Wen-peng Yu, **u-qi Wang, Zi-yao Wang, Zhi-qiang Xu in Scientific Reports (2024)

  2. Article

    Open Access

    Evaluating AI in medicine: a comparative analysis of expert and ChatGPT responses to colorectal cancer questions

    Colorectal cancer (CRC) is a global health challenge, and patient education plays a crucial role in its early detection and treatment. Despite progress in AI technology, as exemplified by transformer-like mode...

    Wen Peng, Yifei feng, Cui Yao, Sheng Zhang, Han Zhuo, Tianzhu Qiu in Scientific Reports (2024)

  3. Article

    Open Access

    Geochronological results from the Zhela Formation volcanics of the Tethyan Himalaya and their implications for the breakup of eastern Gondwana

    The relationship between the Kerguelen mantle plume and the breakup of eastern Gondwana is still debated. The new Zircon SHRIMP U–Pb dating of 139.9 ± 4.6 Ma, as well as previous ages from the Zhela Formation ...

    Jiacheng Liang, Weiwei Bian, **anwei Jiao, Wenxiao Peng, Jiahui Ma in Scientific Reports (2023)

  4. Article

    Open Access

    Exogenous plant growth regulator and foliar fertilizers for phytoextraction of cadmium with Boehmeria nivea [L.] Gaudich from contaminated field soil

    As a enrichment plant, ramie can be used for the phytoremediation of cadmium (Cd)-contaminated soil. However, it is worth exploring the role of plant growth regulators and foliar fertilizers in the process of ...

    Wenxian Peng, Yejun He, Si He, **feng Luo, Yi Zeng, **aoyang Zhang in Scientific Reports (2023)

  5. Article

    Open Access

    Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis

    Extracellular DNA traps (ETs) represent an immune response by which cells release essential materials like chromatin and granular proteins. Previous studies have demonstrated that the transdifferentiation of v...

    Ming Zhai, Shiyu Gong, Peipei Luan, Yefei Shi, Wenxin Kou in Nature Communications (2022)

  6. Article

    Open Access

    Infralimbic medial prefrontal cortex signalling to calbindin 1 positive neurons in posterior basolateral amygdala suppresses anxiety- and depression-like behaviours

    Generalization is a fundamental cognitive ability of organisms to deal with the uncertainty in real-world situations. Excessive fear generalization and impaired reward generalization are closely related to man...

    Huiling Yu, Li** Chen, Huiyang Lei, Guilin Pi, Rui **ong in Nature Communications (2022)

  7. Article

    Open Access

    PIM1 promotes hepatic conversion by suppressing reprogramming-induced ferroptosis and cell cycle arrest

    Protein kinase-mediated phosphorylation plays a critical role in many biological processes. However, the identification of key regulatory kinases is still a great challenge. Here, we develop a trans-omics-base...

    Yangyang Yuan, Chenwei Wang, Xuran Zhuang, Shaofeng Lin in Nature Communications (2022)

  8. Article

    Open Access

    Neuromorphic device based on silicon nanosheets

    Silicon is vital for its high abundance, vast production, and perfect compatibility with the well-established CMOS processing industry. Recently, artificially stacked layered 2D structures have gained tremendo...

    Chenhao Wang, **nyi Xu, **aodong Pi, Mark D. Butala, Wen Huang in Nature Communications (2022)

  9. Article

    Open Access

    A natural uORF variant confers phosphorus acquisition diversity in soybean

    Phosphorus (P) is an essential element for all organisms. Because P fertilizers are a non-renewable resource and high fixation in soils, sustainable agriculture requires researchers to improve crop P acquisiti...

    Zilong Guo, Hongrui Cao, **g Zhao, Shuang Bai, Wenting Peng in Nature Communications (2022)

  10. Article

    Open Access

    Learning aerodynamics with neural network

    We propose a neural network (NN) architecture, the Element Spatial Convolution Neural Network (ESCNN), towards the airfoil lift coefficient prediction task. The ESCNN outperforms existing state-of-the-art NNs ...

    Wenhui Peng, Yao Zhang, Eric Laurendeau, Michel C. Desmarais in Scientific Reports (2022)

  11. Article

    Open Access

    Clinical and genomic features of Chinese lung cancer patients with germline mutations

    The germline mutation landscape in Chinese lung cancer patients has not been well defined. In this study, sequencing data of 1,021 cancer genes of 1,794 Chinese lung cancer patients was analyzed. A total of 11...

    Wenying Peng, Bin Li, ** Li, Lianpeng Chang, **g Bai, Yuting Yi in Nature Communications (2022)

  12. Article

    Open Access

    Upcycling of dynamic thiourea thermoset polymers by intrinsic chemical strengthening

    Thermoset polymers are indispensable but their environmental impact has been an ever-increasing concern given their typical intractability. Although concepts enabling their reprocessing have been demonstrated,...

    Haijun Feng, Ning Zheng, Wenjun Peng, Chujun Ni, Huijie Song in Nature Communications (2022)

  13. Article

    Open Access

    The study of automatic machine learning base on radiomics of non-focus area in the first chest CT of different clinical types of COVID-19 pneumonia

    To explore the possibility of predicting the clinical types of Corona-Virus-Disease-2019 (COVID-19) pneumonia by analyzing the non-focus area of the lung in the first chest CT image of patients with COVID-19 b...

    Hui-Bin Tan, Fei **ong, Yuan-Liang Jiang, Wen-Cai Huang, Ye Wang in Scientific Reports (2020)

  14. Article

    Open Access

    2D MXene-Based Materials for Electrocatalysis

    MXenes, as an emerging 2D material, are expected to exert a great influence on future energy storage and conversion technologies. In this review, we systematically summarize recent advances in MXene-based mate...

    Jiapeng Liu, Wenchao Peng, Yang Li, Fengbao Zhang in Transactions of Tian** University (2020)

  15. Article

    Open Access

    Microbial community structure and functional properties in permanently and seasonally flooded areas in Poyang Lake

    Water level fluctuations are an inherent feature regulating the ecological structures and functions of lakes. It is vital to understand the effects of water level fluctuations on bacterial communities and meta...

    Yang Liu, Ze Ren, **aodong Qu, Min Zhang, Yang Yu, Yuhang Zhang in Scientific Reports (2020)

  16. Article

    Open Access

    Parabolic dependence of the drag coefficient on wind speed from aircraft eddy-covariance measurements over the tropical Eastern Pacific

    In this study, we examine and present the relationship between drag coefficient and wind speed. We used an observational dataset that consists of 806 estimates of the mean flow and fluxes from aircraft eddy-co...

    Zhiqiu Gao, Wenwu Peng, Chloe Y. Gao, Yubin Li in Scientific Reports (2020)

  17. Article

    Open Access

    Introducing national osteopathy practice-based research networks in Australia and New Zealand: an overview to inform future osteopathic research

    Both the Osteopathic Research Innovation Network (ORION) and the Osteopathy Research Connect-New Zealand (ORC-NZ) are practice-based research networks (PBRNs) recently established in Australia and New Zealand....

    Amie Steel, Wenbo Peng, David Sibbritt, Jon Adams in Scientific Reports (2020)

  18. Article

    Open Access

    Integrated Transcriptomics, Proteomics, and Glycomics Reveals the Association between Up-regulation of Sialylated N-glycans/Integrin and Breast Cancer Brain Metastasis

    Breast cancer brain metastasis has been recognized as one of the central issues in breast cancer research. The elucidation of the processes and pathways that mediate this step will provide important clues for ...

    Wen**g Peng, Rui zhu, Shiyue Zhou, Parvin Mirzaei, Yehia Mechref in Scientific Reports (2019)

  19. Article

    Open Access

    The allotetraploid origin and asymmetrical genome evolution of the common carp Cyprinus carpio

    Common carp (Cyprinus carpio) is an allotetraploid species derived from recent whole genome duplication and provides a model to study polyploid genome evolution in vertebrates. Here, we generate three chromosome-...

    Peng Xu, Jian Xu, Guangjian Liu, Lin Chen, Zhixiong Zhou in Nature Communications (2019)

  20. Article

    Open Access

    Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases

    Epstein-Barr virus (EBV) is associated with a number of diseases, including malignancies. Currently, it is not known whether patients with different EBV-associated diseases have different methylation profiles ...

    W. K. Jacky Lam, Peiyong Jiang, K. C. Allen Chan, Wenlei Peng in Nature Communications (2019)

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