90 Result(s)

Article

Correction: Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits

Jiaojiao Hao, Wenhua Fan, Yizhuo Li… in Journal of Experimental & Clinical Cancer … (2024)

Article

Antitumor efficacy and potential mechanism of FAP-targeted radioligand therapy combined with immune checkpoint blockade

Radiotherapy combined with immune checkpoint blockade holds great promise for synergistic antitumor efficacy. Targeted radionuclide therapy delivers radiation directly to tumor sites. LNC1004 is a fibroblast a...

Liang Zhao, Yizhen Pang, Yangfan Zhou… in Signal Transduction and Targeted Therapy (2024)

Article

Molecular landscape and multi-omic measurements of heterogeneity in fetal adenocarcinoma of the lung

Fetal adenocarcinoma of the lung (FLAC) is a rare form of lung adenocarcinoma and was divided into high-grade (H-FLAC) and low-grade (L-FLAC) subtypes. Despite the existence of some small case series studies, ...

Li Sun, Wei Guo, Lei Guo, **aoxi Chen, Haitao Zhou, Shi Yan… in npj Precision Oncology (2024)

Article

Brachytherapy in craniopharyngiomas: a systematic review and meta-analysis of long-term follow-up

Brachytherapy has been indicated as an alternative option for treating cystic craniopharyngiomas (CPs). The potential benefits of brachytherapy for CPs have not yet been clarified. The purpose of this work was...

Li-Yuan Zhang, Wei Guo, Han-Ze Du, Hui Pan, Yun-Chuan Sun, Hui-Juan Zhu… in BMC Cancer (2024)

Article

Safety, immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly: a prospective longitudinal study

The safety and efficacy of COVID-19 vaccines in the elderly, a high-risk group for severe COVID-19 infection, have not been fully understood. To clarify these issues, this prospective study followed up 157 eld...

Hong-Hong Liu, Yunbo **e, Bao-Peng Yang… in Signal Transduction and Targeted Therapy (2024)

Article

Multi-cancer early detection tests: pioneering a revolution in cancer screening

Huiqin Jiang, Wei Guo in Clinical Cancer Bulletin (2024)

Article

Tumor burden score and carcinoembryonic antigen predict outcomes in patients with intrahepatic cholangiocarcinoma following liver resection: a multi‑institutional analysis

The prognostic significance of tumor burden score (TBS) in relation to carcinoembryonic antigen (CEA) has not been investigated among patients undergoing hepatectomy for intrahepatic cholangiocarcinoma (ICC). ...

Jun Fu, Lifang Zheng, Shicuan Tang, Kongying Lin, Shuguo Zheng, **nyu Bi… in BMC Cancer (2024)

Article

Anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab for first-line treatment in advanced natural killer T cell lymphoma

Natural killer T cell lymphoma (NKTCL) is highly aggressive, with advanced stage patients poorly responding to intensive chemotherapy. To explore effective and safe treatment for newly diagnosed advanced stage...

Jie **ong, Shu Cheng, **ao Gao, Shan-He Yu… in Signal Transduction and Targeted Therapy (2024)

Article

Targeting M2-like tumor-associated macrophages is a potential therapeutic approach to overcome antitumor drug resistance

Tumor drug resistance emerges from the interaction of two critical factors: tumor cellular heterogeneity and the immunosuppressive nature of the tumor microenvironment (TME). Tumor-associated macrophages (TAMs...

Shu**g Wang, **grui Wang, Zhiqiang Chen, Jiamin Luo, Wei Guo… in npj Precision Oncology (2024)

Article

The efficacy and safety of vincristine, irinotecan and anlotinib in Epithelioid Sarcoma

Epithelioid sarcoma is a rare soft tissue sarcoma characterized by SMARCB1/INI1 deficiency. Much attention has been paid to the selective EZH2 inhibitor tazemetostat, where other systemic treatments are genera...

Lu **e, **n Sun, Jie Xu, **n Liang, Kuisheng Liu, Kunkun Sun, Rongli Yang… in BMC Cancer (2024)

Article

Multi-omics and Multi-VOIs to predict esophageal fistula in esophageal cancer patients treated with radiotherapy

This study aimed to develop a prediction model for esophageal fistula (EF) in esophageal cancer (EC) patients treated with intensity-modulated radiation therapy (IMRT), by integrating multi-omics features from...

Wei Guo, Bing Li, Wencai Xu, Chen Cheng… in Journal of Cancer Research and Clinical On… (2024)

Article

Impact of perioperative decreased serum albumin level on anastomotic leakage in esophageal squamous cell carcinoma patients treated with neoadjuvant chemotherapy followed by minimally invasive esophagectomy

Anastomotic leakage (AL) is a severe complication following esophagectomy with high mortality. Perioperative decreased serum albumin level is considered a predictive of AL, however, its impact on AL incidence ...

Ying-Jian Wang, **an-Feng **e, Yi-Qiu He, Tao Bao, **an-Dong He, Kun-Kun Li… in BMC Cancer (2023)

Article

Clinical application of ¹⁹²Ir High-Dose-Rate brachytherapy in metastatic lymph nodes of the neck

The objective of this study was to investigate the safety and effectiveness of high-dose-rate brachytherapy as a treatment modality for recurrent or residual neck metastatic lymph nodes following external radi...

Hongling Lu, Yunchuan Sun, Yan Gao, Li **ao, Jianxi Zhou, **aoming Yin… in Discover Oncology (2023)

Article

China Anti-Cancer Association (CACA) guidelines for holistic integrative management of lymphoma (version 2022)

Lymphoma has become a major threat to human health. Fortunately, the diagnosis and treatment of lymphoma have developed rapidly, and research progress has emerged in an endless stream, with new drugs emerging ...

Qingyuan Zhang, Jifeng Feng, Huaqing Wang, Huiqiang Huang… in Holistic Integrative Oncology (2023)

Article

Correction: LncRNA MYLK-AS1 facilitates tumor progression and angiogenesis by targeting miR-424-5p/E2F7 axis and activating VEGF R-2 signaling pathway in hepatocellular carcinoma

Fei Teng, Ju-**ang Zhang, Qi-Meng Chang… in Journal of Experimental & Clinical Cancer … (2023)

Article

Exploratory study of an anti-PD-L1/TGF-β antibody, TQB2858, in patients with refractory or recurrent osteosarcoma and alveolar soft part sarcoma: a report from Chinese sarcoma study group (TQB2858-Ib-02)

Novel and effective immunotherapies are required for refractory or recurrent sarcomas. Transforming growth factor-beta (TGF-β) is a diverse regulatory and fibrogenic protein expressed in multiple sarcoma tumo...

Lu **e, **n Liang, Jie Xu, **n Sun, Kuisheng Liu, Kunkun Sun, Yuan Li… in BMC Cancer (2023)

Article

Anatomic versus non-anatomic resection for early-stage intrahepatic cholangiocarcinoma: a propensity score matching and stabilized inverse probability of treatment weighting analysis

Radical resection is still the most cost-effectiveness curative strategy for intrahepatic cholangiocarcinoma (ICC), but it remains controversial on the survival benefit of anatomic resection (AR). In this stud...

Qiao Ke, Lei Wang, Ziguo Lin, Hongzhi Liu, Jianying Lou, Shuguo Zheng… in BMC Cancer (2023)

Article

Correction: Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells

Zhenlong Yu, Wei Guo, **aochi Ma, Bao**g Zhang, Peipei Dong, Lin Huang… in Molecular Cancer (2023)

Article

Integrated analysis of single-cell and bulk RNA sequencing data reveals an immunostimulatory microenvironment in tumor thrombus of osteosarcoma

Tumor thrombus of bone sarcomas represents a unique reservoir for various types of cancer and immune cells, however, the investigation of tumor thrombus at a single-cell level is very limited. And it is still ...

Tao Ji, Qianyu Shi, Song Mei, Jiuhui Xu, Haijie Liang, Lu **e, Tingting Ren… in Oncogenesis (2023)

Article

Clinical features and prognosis of double primary malignant neoplasms in patients with non-hodgkin lymphoma

To investigate the clinical features, survival, and prognostic factors of patients with double primary malignant neoplasms (DPMNs) comprising non-Hodgkin lymphoma (NHL) and malignant solid tumors. Of the 2352 ...

Zhumei Zhan, Wei Guo, Jia Li, **n Wan, **g Guo, Ou Bai in Discover Oncology (2023)