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Binding and endocytosis of monoterbium transferrin by K562 cells
Using isotopic labeling of human serum apotransferrin, the binding and the endocytosis of monoterbium transferrin (Tbc-apotransferrin, Tbc-apotransferrin-FeN) by K562 cells, a human leukemic cell line, have been ...
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Article
Evaluation of the effect of air pollution control during the Bei**g 2008 Olympic Games using Lidar data
To examine the effect of pollution control measures on Bei**g air quality during the 2008 Olympic Games, this paper analyzes the variation of aerosol extinction coefficient observed with a Dual-wavelength Pol...
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Article
Biological features of novel avian influenza A (H7N9) virus
An initial characterization of the receptor-binding properties of the novel avian influenza A (H7N9) shows that the virus has acquired the ability to bind human receptors while retaining the ability to bind av...
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Article
Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne
Severe acne is a chronic inflammatory skin disorder characterized by widespread inflammatory lesions including nodules, cysts and potential scarring. Here we perform the first genome-wide association study of ...
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Open AccessAssociation of ERCC1 and ERCC2 polymorphisms with colorectal cancer risk in a Chinese population
The ERCC1 and ERCC2 genes are important in repairing DNA damage and genomic instability and are involved in the nucleotide excision repair pathway. We hypothesized that single nucleotide polymorphisms (SNPs) in E...
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Article
Open AccessControlling Dispersion Characteristics of Terahertz Metasurface
Terahertz (THz) metasurfaces have been explored recently due to their properties such as low material loss and ease of fabrication compared to three-dimensional (3D) metamaterials. Although the dispersion prop...
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Article
Open AccessAnatase TiO2 ultrathin nanobelts derived from room-temperature-synthesized titanates for fast and safe lithium storage
Lithium-ion batteries (LIBs) are promising energy storage devices for portable electronics, electric vehicles and power-grid applications. It is highly desirable yet challenging to develop a simple and scalabl...
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Article
Open AccessGenetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous...
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Article
Erratum: Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
Nature 524, 93–96 (2015); doi:10.1038/nature14490 This Letter should have contained an associated Creative Commons statement in the Author Information section. In addition, the Fig. 3c legend should have state...
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Article
Relativistic baryonic jets from an ultraluminous supersoft X-ray source
Persistent low-velocity baryonic jets have been detected from a supersoft X-ray source; the low velocity suggests that these jets have not been launched from a white dwarf, and the persistence speaks against t...
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Article
Open AccessAryl Hydrocarbon Receptor Activates NDRG1 Transcription under Hypoxia in Breast Cancer Cells
Hypoxia has been intensively investigated over the past several decades based on the observations that hypoxic tumors are more resistant to therapy and have a worse prognosis. Previously, we reported that N-my...
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Open AccessA triterpenoid from wild bitter gourd inhibits breast cancer cells
The antitumor activity of 3β,7β,25-trihydroxycucurbita-5,23(E)-dien-19-al (TCD), a triterpenoid isolated from wild bitter gourd, in breast cancer cells was investigated. TCD suppressed the proliferation of MCF-7 ...
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Open AccessSets of serum exosomal microRNAs as candidate diagnostic biomarkers for Kawasaki disease
Although Kawasaki disease is the main cause of acquired heart disease in children, no diagnostic biomarkers are available. We aimed to identify candidate biomarkers for diagnosing Kawasaki disease using serum ...
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Open AccessBone Microarchitecture and Biomechanics of the Necrotic Femoral Head
The mechanism behind osteonecrosis of the femoral head (ONFH) remains unclear. The aim of this study was to explore the pathogenesis of ONFH from a biomechanical standpoint to provide a theoretical basis for i...
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Open AccessFrequent pauses in Escherichia coli flagella elongation revealed by single cell real-time fluorescence imaging
The bacterial flagellum is a large extracellular protein organelle that extrudes from the cell surface. The flagellar filament is assembled from tens of thousands of flagellin subunits that are exported throug...
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Open AccessComprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA fibroblast-like synoviocytes (FLS)...
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Open AccessThe underlying microbial mechanism of epizootic rabbit enteropathy triggered by a low fiber diet
Epizootic rabbit enteropathy (ERE) is reproduced successfully in the present study by feeding rabbits a low-fibre diet, and high-throughput sequencing and quantitative real-time PCR (qPCR) analysis were applie...
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Open AccessComplex wireframe DNA nanostructures from simple building blocks
DNA nanostructures with increasing complexity have showcased the power of programmable self-assembly from DNA strands. At the nascent stage of the field, a variety of small branched objects consisting of a few...
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Article
High-temperature bulk metallic glasses developed by combinatorial methods
Since their discovery in 19601, metallic glasses based on a wide range of elements have been developed2. However, the theoretical prediction of glass-forming compositions is challenging and the discovery of alloy...
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Open AccessComparison of chemical stability and corrosion resistance of group IV metal oxide films formed by thermal and plasma-enhanced atomic layer deposition
The wide applications of ultrathin group IV metal oxide films (TiO2, ZrO2 and HfO2) probably expose materials to potentially reactive etchants and solvents, appealing for extraordinary chemical stability and corr...