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Article
Decreased syntaxin17 expression contributes to the pathogenesis of acute pancreatitis in murine models by impairing autophagic degradation
Acute pancreatitis (AP) is an inflammatory disease of the exocrine pancreas. Disruptions in organelle homeostasis, including macroautophagy/autophagy dysfunction and endoplasmic reticulum (ER) stress, have bee...
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Article
Open AccessField investigation combined with modeling uncovers the ecological heterogeneity of Aedes albopictus habitats for strategically improving systematic management during urbanization
Aedes albopictus is an invasive vector of serious Aedes-borne diseases of global concern. Habitat management remains a critical factor for establishing a cost-effective systematic strategy for sustainable vector ...
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Article
Open AccessMap** global zoonotic niche and interregional transmission risk of monkeypox: a retrospective observational study
Outbreaks of monkeypox have been ongoing in non-endemic countries since May 2022. A thorough assessment of its global zoonotic niche and potential transmission risk is lacking.
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Article
Clonal integration facilitates higher resistance to potentially toxic element stress in invasive alien plants than in natives
Heavy metal (especially for potentially toxic element) contamination in soil has frequently been associated with plant invasion. However, the mechanisms underpinning plant invasion under potentially toxic elem...
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Article
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells
UDP-glucose ceramide glucosyltransferase (UGCG) is the first key enzyme in glycosphingolipid (GSL) metabolism that produces glucosylceramide (GlcCer). Increased UGCG synthesis is associated with cell prolifera...
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Article
Azospirillum Aestuarii sp. nov., a Novel Nitrogen-Fixting and Aerobic Denitrifying Bacteria Isolated from an Estuary of a Freshwater River
A novel Gram-staining negative, aerobic, rod-shaped bacterium, designated strain YIM DDC1T, was isolated from an estuary sediment sample of Dongda River flowing into Dianchi lake in Yunnan, southwest China. The s...
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Article
Open AccessMap** the viruses belonging to the order Bunyavirales in China
Viral pathogens belonging to the order Bunyavirales pose a continuous background threat to global health, but the fact remains that they are usually neglected and their distribution is still ambiguously known. We...
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Article
Open AccessReduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder
The nucleus accumbens (NAc) is considered a hub of reward processing and a growing body of evidence has suggested its crucial role in the pathophysiology of major depressive disorder (MDD). However, inconsiste...
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Article
Superconducting multipole wiggler with large magnetic gap for HEPS-TF
A 16-pole superconducting multipole wiggler with a large gap of 68 mm was designed and fabricated to serve as a multipole wiggler for HEPS-TF. The wiggler consists of 16 pairs of NbTi superconducting coils wit...
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Article
Open AccessDisrupted intrinsic functional brain topology in patients with major depressive disorder
Aberrant topological organization of whole-brain networks has been inconsistently reported in studies of patients with major depressive disorder (MDD), reflecting limited sample sizes. To address this issue, w...
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Article
Open AccessChanges in notifiable infectious disease incidence in China during the COVID-19 pandemic
Nationwide nonpharmaceutical interventions (NPIs) have been effective at mitigating the spread of the novel coronavirus disease (COVID-19), but their broad impact on other diseases remains under-investigated. ...
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Article
Association between anemia and outcome in patients hospitalized for acute heart failure syndromes: findings from Bei**g Acute Heart Failure Registry (Bei**g AHF Registry)
Whether the anemia increases the risk of mortality in patients with acute heart failure (AHF) remains unclear. This study aims to explore the relationship between anemia and outcomes in patients with AHF inclu...
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Article
Open AccessClinical features and outcomes of PComA aneurysms originating from fetal posterior communicating arteries in a single institution
The aim of this study was to retrospectively analyze our experience with the patients who underwent surgical treatment of posterior communicating artery (PComA) aneurysms originating from fetal posterior cereb...
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Article
Detection performance of azimuthal electromagnetic logging while drilling tool in anisotropic media
Azimuthal electromagnetic (EM) logging while drilling (LWD) has been extensively used in high-angle and horizontal (HA/HZ) wells. However, due to the effects of formation anisotropy, accurate geosteering decis...
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Article
Open AccessCorrection to: Promoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)
In the original publication of this manuscript [1], Fig. 6 contains a repeated image in error (the left image of ‘Migration’ and the left image of ‘Invasion’).
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Article
Open AccessDetection performance and inversion processing of logging-while-drilling extra-deep azimuthal resistivity measurements
We present systematic investigations on the physics, detection performance and inversion of logging-while-drilling extra-deep azimuthal resistivity measurements (EDARM). First, the definitions of EDRAM measure...
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Article
Open AccessEvaluation of scrub typhus diagnosis in China: analysis of nationwide surveillance data from 2006 to 2016
Scrub typhus is a life-threatening disease caused by Orientia tsutsugamushi, and specific antimicrobial medicine is available. Early and accurate diagnosis is essential for reducing the risk of severe complicatio...
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Article
Open AccessDevelopment of polyclonal antiserum against movement protein from Potato leafroll virus and its application for the virus detection
The serological method is one of the most important techniques extensively used in crop production to detect different pathogens, especially plant viruses. An antiserum is essential for serological tests. The ...
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Article
Open AccessPromoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)
Esophageal cancer is a high incident cancer worldwide with poor survival and limited therapeutic options. Alterations of microRNAs are common in cancers, and many of these micro RNAs are potential therapeutic ...
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Article
Open AccessBrassica yellows virus’ movement protein upregulates anthocyanin accumulation, leading to the development of purple leaf symptoms on Arabidopsis thaliana
Poleroviruses are widely distributed and often of great economic importance because they cause a variety of symptoms, such as the rolling of young leaves, leaf color changes, and plant decline, in infected pla...
