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Article
Antisense EGFR sequence enhances apoptosis in a human hepatoma cell line BEL-7404
Effects of antisense epidermal growth factor receptor(EGFR) sequence on apoptotic cell death were examined in a human hepatoma cell line BEL-7404 cells. In the cells of JX-1, a sub clone of BEL-7404 stably tra...
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Article
One-Tube Nested RT-PCR Enabled by Using a Plastic Film and its Application for the Rapid Detection of SARS-Virus
A general strategy based on the use of a plastic film that allows reverse transcription and nested-PCR in a single closed-tube has been developed. The reaction mixture for the second PCR amplification is quara...
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Chapter and Conference Paper
An Auto-stopped Hierarchical Clustering Algorithm for Analyzing 3D Model Database
In the research of shape-based 3D model retrieval, the analysis and classification of 3D model database is an important topic for improving the retrieval performance. However, it encounters difficulties due to...
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Article
Open AccessPrognostic relevance of Centromere protein H expression in esophageal carcinoma
Many kinetochore proteins have been shown to be associated with human cancers. The aim of the present study was to clarify the expression of Centromere protein H (CENP-H), one of the fundamental components of ...
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Article
Open AccessUncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks
Network co-regulated modules are believed to have the functionality of packaging multiple biological entities, and can thus be assumed to coordinate many biological functions in their network neighbouring regi...
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Article
Open AccessInteraction proteomics of synapse protein complexes
The brain integrates complex types of information, and executes a wide range of physiological and behavioral processes. Trillions of tiny organelles, the synapses, are central to neuronal communication and inf...
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Article
Open AccessA towards-multidimensional screening approach to predict candidate genes of rheumatoid arthritis based on SNP, structural and functional annotations
According to the Genetic Analysis Workshops (GAW), hundreds of thousands of SNPs have been tested for association with rheumatoid arthritis. Traditional genome-wide association studies (GWAS) have been develop...
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Article
Open AccessPrognostic relevance of Bmi-1 expression and autoantibodies in esophageal squamous cell carcinoma
Overexpression of Bmi-1 has been observed in a variety of cancers, and it has been suggested to be an independent prognostic marker for the patients. The objective of this study was to determine the level of B...
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Article
Open AccessAnti-CDC25B autoantibody predicts poor prognosis in patients with advanced esophageal squamous cell carcinoma
The oncogene CDC25B phosphatase plays an important role in cancer cell growth. We have recently reported that patients with esophageal squamous cell carcinoma (ESCC) have significantly higher serum levels of C...
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Article
Open AccessSequencing of DC-SIGN promoter indicates an association between promoter variation and risk of nasopharyngeal carcinoma in cantonese
The dendritic cell-specific intercellular adhesion molecule 3 grabbing non-integrin (DC-SIGN) is an important pathogen recognition receptor of the innate immune system. DC-SIGN promoter variants play important ro...
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Article
Open AccessSurgical treatment of tricuspid regurgitation after mitral valve surgery: a retrospective study in China
Functional tricuspid regurgitation (TR) occurs in patients with rheumatic mitral valve disease even after mitral valve surgery. The aim of this study was to analyze surgical results of TR after previous succes...
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Article
Open AccessElevated levels of serum amyloid A indicate poor prognosis in patients with esophageal squamous cell carcinoma
Increase of Serum amyloid A (SAA) level has been observed in patients with a variety of cancers. The objective of this study was to determined whether SAA level could be used as a prognostic parameter in patie...
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Article
Open AccessEffects of amino acid substitutions in the VP2 B-C loop on antigenicity and pathogenicity of serotype Asia1 foot-and-mouth disease virus
Foot-and-mouth disease virus (FMDV) exhibits a high degree of antigenic variability. Studies of the antigenic diversity and determination of amino acid changes involved in this diversity are important to the d...
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Article
Open AccessThe expressions of MIF and CXCR4 protein in tumor microenvironment are adverse prognostic factors in patients with esophageal squamous cell carcinoma
Tumor-derived cytokines and their receptors usually take important roles in the disease progression and prognosis of cancer patients. In this survey, we aimed to detect the expression levels of MIF and CXCR4 i...
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Article
Projective Lag Synchronization and Parameter Identification of a New Hyperchaotic System
In this paper, the projective lag synchronization of a new hyperchaotic system with certain/uncertain parameters is addressed. Based on Lyapunov stability theory, a generic and simple controller is designed fo...
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Article
Open AccessIdentification of breast cancer patients based on human signaling network motifs
Identifying breast cancer patients is crucial to the clinical diagnosis and therapy for this disease. Conventional gene-based methods for breast cancer diagnosis ignore gene-gene interactions and thus may lead...
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Article
Open AccessUnraveling the characteristics of microRNA regulation in the developmental and aging process of the human brain
Structure and function of the human brain are subjected to dramatic changes during its development and aging. Studies have demonstrated that microRNAs (miRNAs) play an important role in the regulation of brain...
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Article
Open AccessThe study of rare \( {B_c}\to D_{s,d}^{{\left( * \right)}}l\overline{l} \) decays
In this paper, we study rare decays \( {B_c}\to D_{s,d}^{{\left( * \right)}}l\overline{l} \) within the Standard Model....
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Article
Open AccessReducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer’s disease
Alzheimer’s disease is caused by increased production or reduced clearance of amyloid-β, which results in the formation amyloid-β plaques and triggers a cascade of downstream events leading to progressive neur...
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Article
Open AccessEstablishment of using serum YKL-40 and SCCA in combination for the diagnosis of patients with esophageal squamous cell carcinoma
Elevated serum YKL-40 levels have been observed in various cancers. We evaluated the diagnostic performance of serum YKL-40 alone or in combination with the CEA, CYFRA21-1 and SCCA tumor markers for patients w...
