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Article
Open AccessImproving the accuracy of pre-operative survival prediction in renal cell carcinoma with C-reactive protein
Validated objective biomarkers are needed for patients with renal cell carcinoma (RCC) to guide patient management and define high-risk populations for follow-up or for therapeutic purposes.
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Article
Open AccessHigh-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin’s disease is unlikely to be associated with a major increased risk of secondary MDS/AML
Hodgkin’s disease is curable in the majority of patients, although a proportion of patients are resistant to or relapse after initial therapy. High-dose therapy with autologous stem cell support has become the...
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Article
Combination chemotherapy for intermediate and high grade non-Hodgkin's lymphoma
One hundred and eighteen consecutive adults with newly diagnosed intermediate and high-grade non-Hodgkin's lymphoma were treated with chemotherapy comprising Doxorubicin, Cyclophosphamide, Vincristine and Pred...
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Article
Clinical pharmacokinetics of epirubicin: the importance of liver biochemistry tests
The influence of liver biochemistry tests on epirubicin pharmacokinetics has been investigated in 52 women with advanced breast cancer, 27 of whom had radiologically proven liver metastases. Patients received ...
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Article
Patterns of survival in patients with advanced Hodgkin's disease (HD) treated in a single centre over 20 years
A total of 164 consecutive adults with newly confirmed stage IIIB, IVA or IVB Hodgkin's disease (HD) commenced cyclical combination chemotherapy comprising mustine, vinblastine, prednisolone and procarbazine (...
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Article
High dose cytosine arabinoside in the initial treatment of adults with acute lymphoblastic leukaemia
In a study conducted at St Bartholomew's Hospital between 1972 and 1982, using moderately intensive therapy (OPAL/HEAV'D), a low blast count at presentation (less than 10 x 10(9) 1(-1)) and common ALL (C-ALL) ...
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Article
Monoclonal antibody assay of serum placental alkaline phosphatase in the monitoring of testicular tumours
A monoclonal antibody (H17E2) recognising both placental alkaline phosphatase (PLAP) and testicular PLAP-like alkaline phosphatase was incorporated in a solid phase immunoassay. This was used to measure levels...