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    Article

    Prolonged low dose IL-2 and thalidomide in progressive metastatic renal cell carcinoma with concurrent radiotherapy to bone and/or soft tissue metastasis: a phase II study

    Metastatic renal cell cancer is one of the immuno-sensitive tumors. Apart from the immuno-modulating agents IFNα and IL-2, thalidomide has been reported to be effective in this type of cancer. However, bone me...

    J. M. Kerst, A. Bex, H. Mallo, L. Dewit in Cancer Immunology, Immunotherapy (2005)

  2. Article

    Open Access

    Temozolomide followed by combined immunotherapy with GM-CSF, low-dose IL2 and IFNα in patients with metastatic melanoma

    The purpose of this study is to determine the toxicity and efficacy of temozolomide (TMZ) p.o. followed by subcutaneous (s.c.) low-dose interleukin-2 (IL2), granulocyte–monocyte colony stimulating factor (GM-C...

    G C de Gast, D Batchelor, M J Kersten, F A Vyth-Dreese, J Sein in British Journal of Cancer (2003)