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  1. No Access

    Article

    Dose-Responsive Impacts of Social Frailty on Intrinsic Capacity and Healthy Aging among Community-Dwelling Middle-aged and Older Adults: Stronger Roles of Social Determinants over Biomarkers

    The intricate relationship between social determinants, e.g., social frailty, biomarkers and healthy aging remains largely unexplored, despite the potential for social frailty to impact both intrinsic capacity...

    S.-T. Huang, W.-H. Lu, W.-J. Lee, L.-N. Peng… in The Journal of Frailty & Aging (2024)

  2. No Access

    Article

    Foxp3 is a key downstream regulator of p53-mediated cellular senescence

    The downstream events and target genes of p53 in the process of senescence are not fully understood. Here, we report a novel function of the forkhead transcription factor Foxp3, which is a key player in mediat...

    J-E Kim, J-S Shin, J-H Moon, S-W Hong, D-J Jung, J H Kim, I-Y Hwang, Y J Shin… in Oncogene (2017)

  3. No Access

    Article

    Generic piperacillin/tazobactam is not associated with galactomannan false-positivity in adult patients with cancer: a case–control study

    Recent products of piperacillin/tazobactam (PTZ) from the original manufacturer, previously considered a major cause of galactomannan (GM) false-positivity, are reported not to be related to it. However, data ...

    J.-H. Ko, K. R. Peck, W. J. Lee, J. Y. Lee… in European Journal of Clinical Microbiology … (2015)

  4. No Access

    Article

    Risk factors for cytomegalovirus gastrointestinal diseases in adult patients with cancer

    Cytomegalovirus (CMV) gastrointestinal (GI) disease has been noticed frequently in cancer patients, causing abdominal pain, diarrhea, and GI bleeding. However, little is known about its actual incidence, clini...

    J.-H. Ko, K. R. Peck, W. J. Lee, K. Huh… in European Journal of Clinical Microbiology … (2014)

  5. No Access

    Article

    SVCT-2 in breast cancer acts as an indicator for L-ascorbate treatment

    L-ascorbate (L-ascorbic acid, vitamin C) clearly has an inhibitory effect on cancer cells. However, the mechanism underlying differential sensitivity of cancer cells from same tissue to L-ascorbate is yet to be c...

    S-W Hong, S-H Lee, J-H Moon, J J Hwang, D E Kim, E Ko, H-S Kim, I J Cho… in Oncogene (2013)

  6. No Access

    Article

    Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-κB pathway

    Visfatin is an adipokine that is highly expressed in visceral fat. Plasma levels of visfatin have been reported to be higher in subjects with obesity and/or type 2 diabetes mellitus. However, the role of visfa...

    W-J Lee, C-S Wu, H Lin, I-T Lee, C-M Wu, J-J Tseng… in International Journal of Obesity (2009)

  7. No Access

    Article

    Cell cycle and immune-related processes are significantly altered in chronic GVHD

    Currently, the pathogenesis of chronic GVHD is unclear. To elucidate the molecular characteristics underlying chronic GVHD, we analyzed the gene expression profiles of 21 mononuclear cell samples from allogene...

    S J Oh, S B Cho, S-H Park, C Z Piao, S M Kwon, I Kim… in Bone Marrow Transplantation (2008)

  8. No Access

    Article

    Serum testosterone level and related metabolic factors in men over 70 years old

    Background: Sex hormone decline remarkably decreases metabolic function in elderly men. Many degenerative diseases may relate to testosterone deficiency. Objective: To evaluate the serum ...

    Y. J. Tang, W. J. Lee, Y. T. Chen, P. H. Liu… in Journal of Endocrinological Investigation (2007)

  9. No Access

    Article

    Adiponectin mRNA levels in the abdominal adipose depots of nondiabetic women

    BACKGROUND: The human adiponectin gene has been implicated in the pathophysiology of obesity, type II diabetes mellitus, dyslipidemia and atherosclerosis. Investigation of the physiological functions of the adipo...

    W-S Yang, M-H Chen, W-J Lee, K-C Lee, C-L Chao… in International Journal of Obesity (2003)

  10. Article

    Islet cell autoimmunity and mitochondrial DNA mutation in Korean subjects with typical and atypical Type I diabetes

    The 1997 American Diabetes Association classification of diabetes mellitus included a subset of Type I diabetic patients who do not need insulin for several years but eventually progress to complete insulin d...

    W. J. Lee, H. W. Lee, J. P. Palmer, K. S. Park, H. K. Lee, J. Y. Park… in Diabetologia (2001)

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  11. Article

    35th Annual Meeting of the European Association for the Study of Diabetes

    A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang… in Diabetologia (1999)

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