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Article
Bone marrow transplants from mismatched related and unrelated donors for severe aplastic anemia
For patients with acquired severe aplastic anemia without a matched sibling donor and not responding to immunosuppressive treatment, bone marrow transplantation from a suitable alternative donor is often attem...
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Article
Clinically demonstrable anti-autoimmunity mediated by allogeneic immune cells favorably affects outcome after stem cell transplantation in human autoimmune diseases
To determine the role of allogeneic, autologous and syngeneic hemopoietic stem cell transplantation (SCTx) as a treatment for severe autoimmune disease (AID) we performed a literature search employing Medline,...
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Article
Long-term outcome and quality of life of patients who are alive and in complete remission more than two years after allogeneic and syngeneic stem cell transplantation
We assessed long-term outcome in 155 patients who had undergone an allogeneic/syngeneic stem cell transplant (SCT) and were in complete remission for more than 2 years after transplant. Probability of late tra...
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Article
Long-term clinical and molecular remission after allogeneic stem cell transplantation (SCT) in patients with poor prognosis non-Hodgkin's lymphoma
From 1987 to 1999 35 patients with poor prognosis non-Hodgkin's lymphoma (NHL) underwent allogeneic stem cell transplantation (SCT) at the University Hospitals of Vienna and Graz. Initial biopsy specimens were...
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Article
Anaplastic squamous cell carcinoma (SCC) in a patient with chronic cutaneous graft-versus-host disease (GVHD)
We describe an allogeneic bone marrow (BM) recipient who developed aggressive, metastasizing squamous cell cancer (SCC) of the skin, and discuss possible risk factors in the development of this secondary solid...
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Article
Leukemia-free survival and mortality in patients with refractory or relapsed acute leukemia given marrow transplants from sibling and unrelated donors
Between April 1982 and February 1997 39 patients (24 male, 15 female) with refractory acute leukemia and a median age of 31 years (19–51 years) received allogeneic marrow grafts from an HLA-identical sibling (n =...
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Article
Excellent long-term survival after allogeneic marrow transplantation in patients with severe aplastic anemia
Between 1982 and 1996, 20 patients (10 male, 10 female) with severe aplastic anemia (SAA) with a median age of 25 years (17–37 years), received grafts from an HLA-identical sibling (n = 17), HLA-identical unrelat...
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Chapter and Conference Paper
Durch Salazosulfapyridin (Salazopyrin, Azulfidine) induzierte Folsäuremangelanämie
Salazosulfapyridin (Salazopyrin) wird seit 1942 in der Behandlung von chronisch entzündlichen Erkrankungen des Dickdarms verwendet. Wenn auch etwa ein Fünftel der behandelten Patienten über geringfügige Nebenw...
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Chapter and Conference Paper
Zur Produktion von Granulocyten-Makrophagen-kolonien-stimulierenden Faktoren (GM-CSF) in vitro und in vivo nach Endotoxinaktivierung: Nachweis für abnorme humorale Regulationsbedingungen für leukamische Blasten bei Patienten mit akuter Myelose
Akut leukämische Blasten sind durch einen Differenzierungsdefekt gekennzeichnet, der die Ausreifung zu Funktionszellen verhindert und der Zelle durch erhöhtes Prolifera-tionspotential Tumorcharakter verleiht. Im ...