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    PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia

    Protein arginine methyltransferase 5 (PRMT5) has emerged as a promising cancer drug target, and three PRMT5 inhibitors are currently in clinical trials for multiple malignancies. In this study, we investigated...

    Aliaksandra Radzisheuskaya, Pavel V. Shliaha in Nature Structural & Molecular Biology (2019)