6 Result(s)
within
Vivian Lee
Cancer Research
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Article
Multiscale reverse engineering of the human ocular surface
Here we present a miniaturized analog of a blinking human eye to reverse engineer the complexity of the interface between the ocular system and the external environment. Our model comprises human cells and pro...
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Article
Open AccessDeep learning networks find unique mammographic differences in previous negative mammograms between interval and screen-detected cancers: a case-case study
To determine if mammographic features from deep learning networks can be applied in breast cancer to identify groups at interval invasive cancer risk due to masking beyond using traditional breast density meas...
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Article
IL-17E, a proinflammatory cytokine, has antitumor efficacy against several tumor types in vivo
Interleukin-17E (IL-17E) belongs to a novel family of cytokines that possess significant homology to IL-17. IL-17E has potent inflammatory effects in vitro and in vivo. Overexpression of IL-17E in mice results...
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Article
Virulizin® induces production of IL-17E to enhance antitumor activity by recruitment of eosinophils into tumors
Virulizin® has demonstrated strong antitumor efficacy in a variety of human tumor xenograft models including melanoma, pancreatic cancer, breast cancer, ovarian cancer and prostate cancer. Our previous studies ha...
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Article
Virulizin, a novel immunotherapy agent, activates NK cells through induction of IL-12 expression in macrophages
Virulizin, a novel biological response modifier, has demonstrated significant antitumor efficacy in a variety of human tumor xenograft models including melanoma, pancreatic cancer, breast cancer, ovarian cance...
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Article
NK cell activation and tumor infiltration are involved in the antitumor mechanism of Virulizin
Previous studies have demonstrated antitumor efficacy of Virulizin in several human tumor xenograft models and a critical role for macrophages in the antitumor mechanism of Virulizin. Although there is growing...
