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  1. Article

    Open Access

    Efficacy and safety of bemcentinib in patients with advanced myelodysplastic neoplasms or acute myeloid leukemia failing hypomethylating agents- the EMSCO phase II BERGAMO trial

    A. S. Kubasch, P. Peterlin, T. Cluzeau, K. S. Götze, K. Sockel, R. Teipel in Leukemia (2023)

  2. Article

    Open Access

    Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach to classification of patients with t-MDS

    In the current World Health Organization (WHO)-classification, therapy-related myelodysplastic syndromes (t-MDS) are categorized together with therapy-related acute myeloid leukemia (AML) and t-myelodysplastic...

    A. Kuendgen, M. Nomdedeu, H. Tuechler, G. Garcia-Manero, R. S. Komrokji in Leukemia (2021)

  3. Article

    Correction: CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    I. Tirado-Gonzalez, E. Czlonka, A. Nevmerzhitskaya, D. Soetopo, E. Bergonzani in Leukemia (2021)

  4. Article

    Open Access

    CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC

    I Tirado-Gonzalez, E Czlonka, A Nevmerzhitskaya, D Soetopo, E Bergonzani in Leukemia (2018)

  5. No Access

    Article

    Characteristics and outcome of patients with therapy-related acute promyelocytic leukemia front-line treated with or without arsenic trioxide

    Therapy-related acute promyelocytic leukemia (t-APL) is relatively rare, with limited data on outcome after treatment with arsenic trioxide (ATO) compared to standard intensive chemotherapy (CTX). We evaluated...

    S Kayser, J Krzykalla, M A Elliott, K Norsworthy, P Gonzales, R K Hills in Leukemia (2017)

  6. No Access

    Article

    Evolution of NPM1-negative therapy-related myelodysplastic syndromes following curative treatment of NPM1-mutant AML

    S Herold, K Sockel, C Sayehli, R Herbst, U Dührsen, U Oelschlägel, A Böttner in Leukemia (2017)

  7. Article

    Open Access

    A phase 3 randomized placebo-controlled trial of darbepoetin alfa in patients with anemia and lower-risk myelodysplastic syndromes

    The use of darbepoetin alfa to treat anemia in patients with lower-risk myelodysplastic syndromes (MDS) was evaluated in a phase 3 trial. Eligible patients had low/intermediate-1 risk MDS, hemoglobin ⩽10 g/dl,...

    U Platzbecker, A Symeonidis, E N Oliva, J S Goede, M Delforge, J Mayer, B Slama in Leukemia (2017)

  8. No Access

    Article

    Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient

    S Herold, M Kuhn, M v Bonin, T Stange, U Platzbecker, J Radke, T Lange in Leukemia (2017)

  9. No Access

    Article

    Myelodysplastic syndromes and bone loss in mice and men

    H Weidner, M Rauner, F Trautmann, J Schmitt, E Balaian, A Mies, S Helas in Leukemia (2017)

  10. No Access

    Article

    Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis

    Myeloproliferative neoplasm (MPN)-associated myelofibrosis is a MPN characterized by bone marrow fibrosis, cytopenias, splenomegaly and constitutional symptoms. Pomalidomide, an immune-modifying drug, is repor...

    R F Schlenk, F Stegelmann, A Reiter, E Jost, N Gattermann, H Hebart, C Waller in Leukemia (2017)

  11. No Access

    Article

    Prevalence, clonal dynamics and clinical impact of TP53 mutations in patients with myelodysplastic syndrome with isolated deletion (5q) treated with lenalidomide: results from a prospective multicenter study of the german MDS study group (GMDS)

    M Mossner, J-C Jann, D Nowak, U Platzbecker, A Giagounidis, K Götze, A Letsch in Leukemia (2016)

  12. No Access

    Article

    Results of a multicenter prospective phase II trial investigating the safety and efficacy of lenalidomide in patients with myelodysplastic syndromes with isolated del(5q) (LE-MON 5)

    E Schuler, A Giagounidis, D Haase, K Shirneshan, G Büsche, U Platzbecker in Leukemia (2016)

  13. Article

    Open Access

    Bleeding, thrombosis, and anticoagulation in myeloproliferative neoplasms (MPN): analysis from the German SAL-MPN-registry

    Patients with Ph-negative myeloproliferative neoplasms (MPN), such as polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), are at increased risk for thrombosis/thromboemboli...

    A. Kaifie, M. Kirschner, D. Wolf, C. Maintz, M. Hänel in Journal of Hematology & Oncology (2016)

  14. Article

    Open Access

    Clonal architecture of del(5q) myelodysplastic syndromes: aberrant CD5 or CD7 expression within the myeloid progenitor compartment defines a subset with high clonal burden

    U Oelschlaegel, M Alexander Röhnert, B Mohr, K Sockel, S Herold, G Ehninger in Leukemia (2016)

  15. No Access

    Article

    Clofarabine salvage therapy before allogeneic hematopoietic stem cell transplantation in patients with relapsed or refractory AML: results of the BRIDGE trial

    In patients with relapsed or refractory (r/r) acute myeloid leukemia (AML), long-term disease control can only be achieved by allogeneic hematopoietic stem cell transplantation (HSCT). We studied the safety an...

    J M Middeke, R Herbst, S Parmentier, G Bug, M Hänel, G Stuhler in Leukemia (2016)

  16. No Access

    Article

    Frequency and prognostic impact of casein kinase 1A1 mutations in MDS patients with deletion of chromosome 5q

    M Heuser, M Meggendorfer, M M A Cruz, J Fabisch, S Klesse, L Köhler, G Göhring in Leukemia (2015)

  17. No Access

    Article

    Which prognostic score in MDS? Both!

    U Platzbecker in Leukemia (2015)

  18. No Access

    Article

    Hematopoietic cell transplantation in patients with intermediate and high-risk AML: results from the randomized Study Alliance Leukemia (SAL) AML 2003 trial

    The optimal timing of allogeneic hematopoietic stem cell transplantation (HCT) in acute myeloid leukemia (AML) is controversial. We report on 1179 patients with a median age of 48 years who were randomized upf...

    J Schetelig, M Schaich, K Schäfer-Eckart, M Hänel, W E Aulitzky, H Einsele in Leukemia (2015)

  19. Article

    Open Access

    Myelodysplasia is in the niche: novel concepts and emerging therapies

    Myelodysplastic syndromes (MDSs) represent clonal disorders mainly of the elderly that are characterized by ineffective hematopoiesis and an increased risk of transformation into acute myeloid leukemia. The pa...

    E Bulycheva, M Rauner, H Medyouf, I Theurl, M Bornhäuser, L C Hofbauer in Leukemia (2015)

  20. Article

    Open Access

    Relationship of different platelet response criteria and patient outcomes in a romiplostim myelodysplastic syndromes trial

    U Platzbecker, M A Sekeres, H Kantarjian, A Giagounidis, G J Mufti, C Jia in Leukemia (2014)

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