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Article
Symptom- und Belastungserfassung mit MIDOS oder IPOS – Kennzahl Symptom- und Bedarfserfassung, KeSBa-Projekt
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Article
Increasing intensity of therapies assigned at diagnosis does not improve survival of adults with acute myeloid leukemia
We randomized 3375 adults with newly diagnosed acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome to test whether increasingly intensive chemotherapies assigned at study-entry and analyzed on a...
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Article
Azacitidine in combination with intensive induction chemotherapy in older patients with acute myeloid leukemia: The AML-AZA trial of the study alliance leukemia
DNA methylation changes are a constant feature of acute myeloid leukemia. Hypomethylating drugs such as azacitidine are active in acute myeloid leukemia (AML) as monotherapy. Azacitidine monotherapy is not cur...
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Article
The emergence of a C/EBPα mutation in the clonal evolution of MDS towards secondary AML
Recently, mutations in the transcription factor CCAAT/ enhancer binding protein alpha (C/EBPα) have been described in acute myeloid leukemia (AML). We performed a mutational analysis of the C/EBPα gene in the ...
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Chapter and Conference Paper
Real-Time RT-PCR for the Detection and Quantification of AML1/MTG8 Fusion Transcripts in Patients with t(8;21) Positive AML
AML1/MTG8 was quantified relative to the expression of the GAPDH housekee** gene by real-time RT-PCR in 22 patients with t(8;21) positive AML at initial diagnosis and in seven of these patients also during/a...
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Article
Unreifzellige myeloische Leukämie
Die klinischen Befunde von 14 Patienten mit unreifzelliger myeloischer Leukämie werden in knapper Form mitgeteilt. An den leukämischen Zellen (Myeloblasten, Promyelozyten) wurden folgende Untersuchungen durchg...
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