5 Result(s)
within
Tu Bao Ho
Life Sciences
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Article
Open AccessA semi–supervised tensor regression model for siRNA efficacy prediction
Short interfering RNAs (siRNAs) can knockdown target genes and thus have an immense impact on biology and pharmacy research. The key question of which siRNAs have high knockdown ability in siRNA research remai...
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Article
Open AccessA nucleosomal approach to inferring causal relationships of histone modifications
Histone proteins are subject to various posttranslational modifications (PTMs). Elucidating their functional relationships is crucial toward understanding many biological processes. Bayesian network (BN)-based...
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Article
Open AccessSequence-dependent histone variant positioning signatures
Nucleosome, the fundamental unit of chromatin, is formed by wrap** nearly 147bp of DNA around an octamer of histone proteins. This histone core has many variants that are different from each other by their b...
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Article
Open AccessCharacterizing nucleosome dynamics from genomic and epigenetic information using rule induction learning
Eukaryotic genomes are packaged into chromatin, a compact structure containing fundamental repeating units, the nucleosomes. The mobility of nucleosomes plays important roles in many DNA-related processes by r...
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Article
Open AccessFinding microRNA regulatory modules in human genome using rule induction
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules (20–24 nt), which are believed to participate in repression of gene expression. They play important roles in several biological processes (e.g. ...
