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  1. No Access

    Article

    Chronic neutrophilic leukemia preceded by myelodysplastic syndromes

    Chronic neutrophilic leukemia (CNL) is primarily diagnosed by excluding myelodysplastic syndromes (MDS). We report the case of a patient who developed secondary CNL 3 years after hypoplastic MDS. We used dropl...

    Yuta Baba, Tsuyoshi Nakamaki, Hirotaka Sakai… in International Journal of Hematology (2023)

  2. No Access

    Article

    Increased serum C-reactive protein is an adverse prognostic factor in low-risk myelodysplastic syndromes

    Inflammatory cytokines play a role in hematopoiesis and development of myelodysplastic syndromes (MDS). Although increased serum levels of inflammatory cytokines are associated with poor survival in MDS patien...

    Yuta Baba, Bungo Saito, Shotaro Shimada… in International Journal of Hematology (2021)

  3. No Access

    Article

    Characteristics and predictors of post-transplant-associated hemophagocytic lymphohistiocytosis in adults

    Hemophagocytic lymphohistiocytosis (HLH) is an uncontrolled hyperinflammatory disorder driven by an overactive immune system that results in high mortality. Post-transplant-associated hemophagocytic lymphohist...

    Norimichi Hattori, Misuzu Sato, Yuka Uesugi… in International Journal of Hematology (2021)

  4. No Access

    Article

    Elevated C-reactive protein level is associated with poor prognosis in follicular lymphoma patients undergoing rituximab-containing chemotherapy

    Although follicular lymphoma (FL) is a pathological entity characterized by relatively uniform histological and molecular findings, its clinical course is highly variable. Establishment of therapeutic strategi...

    Yukiko Kawaguchi, Bungo Saito, Ayaka Nakata… in International Journal of Hematology (2020)

  5. No Access

    Article

    Impact of CD123 expression, analyzed by immunohistochemistry, on clinical outcomes in patients with acute myeloid leukemia

    Aberrant expression of the interleukin-3 receptor alpha chain (IL3RA or CD123) is frequently observed in patients with a subset of leukemic disorders, including acute myeloid leukemia (AML), particularly in le...

    Nana Arai, Mayumi Homma, Maasa Abe, Yuta Baba… in International Journal of Hematology (2019)

  6. No Access

    Article

    Efficacy of palonosetron to prevent delayed nausea and vomiting in non-Hodgkin’s lymphoma patients undergoing repeated cycles of the CHOP regimen

    Few studies have investigated the effect of palonosetron on delayed chemotherapy-induced nausea and vomiting in lymphoma patients receiving the CHOP regimen. We conducted a prospective clinical trial to assess...

    Bungo Saito, Hidetoshi Nakashima, Maasa Abe, So Murai… in Supportive Care in Cancer (2018)

  7. No Access

    Article

    Dynamics of clonal evolution in myelodysplastic syndromes

    Jaroslaw Maciejewski, Seishi Ogawa and colleagues examine the clonal dynamics of myelodysplastic syndromes (MDS) by analyzing whole-exome and targeted sequencing data from a large patient collection. They find...

    Hideki Makishima, Tetsuichi Yoshizato, Kenichi Yoshida… in Nature Genetics (2017)

  8. No Access

    Article

    Integrated molecular analysis of adult T cell leukemia/lymphoma

    Seishi Ogawa and colleagues report the results of a large-scale sequencing study of adult T cell leukemia/lymphoma. They find recurrent alterations enriched for T cell receptor/NF-κB signaling, T cell traffick...

    Keisuke Kataoka, Yasunobu Nagata, Akira Kitanaka, Yuichi Shiraishi… in Nature Genetics (2015)

  9. No Access

    Article

    Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

    The cohesin complex mediates sister chromatid cohesion during cell division. Now, Seishi Ogawa and colleagues report largely mutually exclusive mutations in multiple members of the cohesin complex in acute mye...

    Ayana Kon, Lee-Yung Shih, Masashi Minamino, Masashi Sanada… in Nature Genetics (2013)

  10. No Access

    Article

    Improvement of the thermal amplitude after rituximab treatment for cold agglutinin disease with Waldenström’s macroglobulinemia

    Norimichi Hattori, Noriko Ishii, Hirotsugu Ariizumi, Daisuke Adachi… in Annals of Hematology (2010)

  11. No Access

    Article

    Megakaryopoiesis and platelet function in polycythemia vera and essential thrombocythemia patients with JAK2 V617F mutation

    Patients with Ph chromosome negative myeloproliferative disease (Ph-MPD) have an increased risk of vascular complications. It remains controversial whether patients with the JAK2 V617F mutation (V617F) exhibit...

    Norimichi Hattori, Kunihiko Fukuchi… in International Journal of Hematology (2008)

  12. No Access

    Article

    Acute Respiratory Distress Syndrome during the Third Infusion of Rituximab in a Patient with Follicular Lymphoma

    We present the case of a 66-year-old man with follicular lymphoma who developed acute respiratory distress syndrome (ARDS) during a third infusion of rituximab. High fever, tachypnea, and progressive hypoxemia...

    Bungo Saito, Tsuyoshi Nakamaki, Daisuke Adachi… in International Journal of Hematology (2004)