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Article
Open AccessEye movements in patients in early psychosis with and without a history of cannabis use
It is unclear whether early psychosis in the context of cannabis use is different from psychosis without cannabis. We investigated this issue by examining whether abnormalities in oculomotor control differ bet...
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Article
Open AccessAssociation of cannabis with glutamatergic levels in patients with early psychosis: Evidence for altered volume striatal glutamate relationships in patients with a history of cannabis use in early psychosis
The associative striatum, an established substrate in psychosis, receives widespread glutamatergic projections. We sought to see if glutamatergic indices are altered between early psychosis patients with and w...
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Article
Open AccessEffect of single dose N-acetylcysteine administration on resting state functional connectivity in schizophrenia
There is interest in employing N-acetylcysteine (NAC) in the treatment of schizophrenia, but investigations of the functional signatures of its pharmacological action are scarce.
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Article
Open AccessEffects of N-acetylcysteine on brain glutamate levels and resting perfusion in schizophrenia
N-Acetylcysteine (NAC) is currently under investigation as an adjunctive treatment for schizophrenia. The therapeutic potential of NAC may involve modulation of brain glutamate function, but its effects on brai.....
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Article
Dysfunctional Striatal Systems in Treatment-Resistant Schizophrenia
The prevalence of treatment-resistant schizophrenia points to a discrete illness subtype, but to date its pathophysiologic characteristics are undetermined. Information transfer from ventral to dorsal striatum...
