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  1. No Access

    Article

    Untargeted metabolomics analysis of ischemia–reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats

    The effects of exercise on the heart and its resistance to disease are well-documented. Recent studies have identified that exercise-induced resistance to arrhythmia is due to the preservation of mitochondrial...

    Traci L. Parry, Joseph W. Starnes, Sara K. O’Neal, James R. Bain… in Metabolomics (2017)

  2. No Access

    Article

    Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism

    Older patients are more likely to acquire and die from acute respiratory distress syndrome (ARDS) and muscle weakness may be more clinically significant in older persons. Recent data implicate muscle ring fing...

    D. Clark Files, Amro Ilaiwy, Traci L. Parry, Kevin W. Gibbs, Chun Liu… in Metabolomics (2016)

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    Article

    Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo

    Chronic hypersecretion of the 37 amino acid amylin is common in type 2 diabetics (T2D). Recent studies implicate human amylin aggregates cause proteotoxicity (cell death induced by misfolded proteins) in both ...

    Amro Ilaiwy, Miao Liu, Traci L. Parry, James R. Bain… in Metabolomics (2016)