4 Result(s)
within
English
Microbiology
Tracey A. Rouault
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Article
An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein
Post-transcriptional regulation of genes important in iron metabolism, ferritin and the transferrin receptor (TfR), is achieved through regulated binding of a cytosolic protein, the iron-responsive element bin...
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Article
Metabolic regulation of citrate and iron by aconitases: role of iron–sulfur cluster biogenesis
Iron and citrate are essential for the metabolism of most organisms, and regulation of iron and citrate biology at both the cellular and systemic levels is critical for normal physiology and survival. Mitochon...
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Article
Open AccessInsertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis
Despite the prominence of iron–sulfur cluster (ISC) proteins in bioenergetics, intermediary metabolism, and redox regulation of cellular, mitochondrial, and nuclear processes, these proteins have been given sc...
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Article
Open AccessThe indispensable role of mammalian iron sulfur proteins in function and regulation of multiple diverse metabolic pathways
In recent years, iron sulfur (Fe–S) proteins have been identified as key players in mammalian metabolism, ranging from long-known roles in the respiratory complexes and the citric acid cycle, to more recently ...
