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Metabolic regulation of citrate and iron by aconitases: role of iron–sulfur cluster biogenesis

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  1. Article

    Open Access

    The indispensable role of mammalian iron sulfur proteins in function and regulation of multiple diverse metabolic pathways

    In recent years, iron sulfur (Fe–S) proteins have been identified as key players in mammalian metabolism, ranging from long-known roles in the respiratory complexes and the citric acid cycle, to more recently ...

    Tracey A. Rouault in BioMetals (2019)

  2. Article

    Open Access

    Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis

    Despite the prominence of iron–sulfur cluster (ISC) proteins in bioenergetics, intermediary metabolism, and redox regulation of cellular, mitochondrial, and nuclear processes, these proteins have been given sc...

    Helge Uhrigshardt, Tracey A. Rouault in JBIC Journal of Biological Inorganic Chemi… (2013)