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  1. No Access

    Article

    Iron metabolism in the CNS: implications for neurodegenerative diseases

  2. Iron homeostasis in the CNS operates in parallel with systemic iron homeostasis, because iron must cross the blood–brain barrier or blood–cerebrospinal fluid b...

    3. Tracey A. Rouault in Nature Reviews Neuroscience (2013)

  3. No Access

    Article

    Reply to “Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse”

    Manik C Ghosh, Hayden Ollivierre-Wilson, Sharon Cooperman… in Nature Genetics (2006)

  4. No Access

    Article

    Iron on the brain

    Accumulations of iron are often detected in the brains of people suffering from neurodegenerative diseases. But it is often not known whether such accumulations contribute directly to disease progression. The ...

    Tracey A. Rouault in Nature Genetics (2001)

  5. No Access

    Article

    Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

    In mammalian cells, regulation of the expression of proteins involved in iron metabolism is achieved through interactions of iron-sensing proteins known as iron regulatory proteins (IRPs), with transcripts tha...

    Timothy LaVaute, Sophia Smith, Sharon Cooperman, Kazuhiro Iwai… in Nature Genetics (2001)