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    Article

    Iron-sulfur proteins hiding in plain sight

    Recent studies suggest that iron-sulfur (Fe-S) proteins may be unexpectedly abundant and functionally diverse in mammalian cells, but their identification still remains difficult. The use of informatics along ...

    Tracey A Rouault in Nature Chemical Biology (2015)

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    Article

    The role of iron regulatory proteins in mammalian iron homeostasis and disease

    Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are mammalian proteins that register cytosolic iron concentrations and post-transcriptionally regulate expression of iron metabolism genes to optimize cellular ...

    Tracey A Rouault in Nature Chemical Biology (2006)

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    Article

    Linking physiological functions of iron

    Iron-sulfur clusters and hemes are two iron-containing prosthetic groups involved in important physiological functions. Identification of the gene responsible for anemia in a mutant zebrafish has revealed an u...

    Tracey A Rouault in Nature Chemical Biology (2005)