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  1. Article

    Open Access

    Gefitinib exposure and occurrence of interstitial lung disease in Japanese patients with non-small-cell lung cancer

    A prospective, multicenter, large-scale cohort with a nested case–control study (NCT00252759) was conducted to identify and quantify risk factors for interstitial lung disease (ILD) in Japanese patients with n...

    Toshio Kawata, Mitsuo Higashimori, Yohji Itoh in Cancer Chemotherapy and Pharmacology (2019)

  2. Article

    Open Access

    Safety and tolerability of the olaparib tablet formulation in Japanese patients with advanced solid tumours

    This was the first Phase I study to assess the safety and tolerability of the tablet formulation of olaparib (Lynparza™), an oral poly(ADP-ribose) polymerase inhibitor, in Japanese patients with advanced solid...

    Kan Yonemori, Kenji Tamura, Makoto Kodaira in Cancer Chemotherapy and Pharmacology (2016)

  3. Article

    Open Access

    Safety and tolerability of AZD5363 in Japanese patients with advanced solid tumors

    Investigate the safety and tolerability of AZD5363 and define a recommended dose for evaluation in Japanese patients with advanced solid malignancies.

    Kenji Tamura, Jun Hashimoto, Yuko Tanabe in Cancer Chemotherapy and Pharmacology (2016)