1 Result(s)

Article

Onapristone Extended Release: Safety Evaluation from Phase I–II Studies with an Emphasis on Hepatotoxicity

Antiprogestins have demonstrated promising activity against breast and gynecological cancers, but liver-related safety concerns limited the advancement of this therapeutic class. Onapristone is a full progeste...

James H. Lewis, Paul H. Cottu, Martin Lehr, Evan Dick, Todd Shearer… in Drug Safety (2020)