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Article
Open AccessSevere Tick-Borne Encephalitis (TBE) in a Patient with X-Linked Agammaglobulinemia; Treatment with TBE Virus IgG Positive Plasma, Clinical Outcome and T Cell Responses
A patient with X-linked agammaglobulinemia (XLA) and severe tick-borne encephalitis (TBE) was treated with TBE virus (TBEV) IgG positive plasma. The patient’s clinical response, humoral and cellular immune res...
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Article
Open AccessCOVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system
SARS-CoV-2 uses ACE2, an inhibitor of the Renin-Angiotensin-Aldosterone System (RAAS), for cellular entry. Studies indicate that RAAS imbalance worsens the prognosis in COVID-19. We present a consecutive retro...
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Article
Open AccessExpanding the etiologic spectrum of spastic ataxia syndrome: chronic infection with human T lymphotropic virus type 1
Human T-lymphotropic virus type-1 (HTLV-1) is a neglected infection most often associated with an indolent process. However, a subset of HTLV-1 seropositive patients face the risk to develop life-threatening T...
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Article
Open AccessEnlarged perivascular spaces in multiple sclerosis on magnetic resonance imaging: a systematic review and meta-analysis
Perivascular spaces can become detectable on magnetic resonance imaging (MRI) upon enlargement, referred to as enlarged perivascular spaces (EPVS) or Virchow-Robin spaces. EPVS have been linked to small vessel...
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Article
Open AccessRare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report
Developmental dyslexia (DD) is a neurodevelopmental learning disorder with high heritability. A number of candidate susceptibility genes have been identified, some of which are linked to the function of the ci...
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Article
Open AccessMap** of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism
There is a need for methods that distinguish Parkinson’s disease (PD) from progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), which have similar characteristics in the early stages of the ...
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Article
Open AccessRepeatability and reproducibility of FreeSurfer, FSL-SIENAX and SPM brain volumetric measurements and the effect of lesion filling in multiple sclerosis
To compare the cross-sectional robustness of commonly used volumetric software and effects of lesion filling in multiple sclerosis (MS).