2,638 Result(s)
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Ting **g
Biomedicine
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Chapter
Einfluß der Alkaliionen auf die Ca++-Speicherung in Mitochondrien und Vesikeln / Contribution to the Discussion—Effect of Ions of Alkalis on the Uptake of Ca++ by Mitochondria and Vesicles
An isolierten Mitochondrien des Herzmuskels wird die Fähigkeit der Calciumspeieherung durch Senkung des K+ /Na+ -Quotienten des Inkubationsmediums vermindert [1]. Entsprechende Beobachtungen lassen sich auch an i...
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Einfluß der Alkaliionen auf die Ca++-Speicherung in Mitochondrien und Vesikeln
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Article
Tissue NAD Levels and the Response to Irradiation or Cytotoxic Drugs
It has been shown that when 32P counting from a tumour is continuous peaks in the count rate can sometimes be induced by large doses of nicotinic acid, nicotinic acid, nicotinamide or 3-acetylpyridine, but not by...
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The Acid Soluble Disulphide and Mixed Disulphide Levels of Some Normal Tissues and Transplanted Tumours
The acid soluble disulphides and mixed disulphides of a range of normal rat and mouse tissues and a number of transplanted rat or mouse tumours were measured. The result were considered in relation to other wo...
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Tissue Ty** in Human Kidney Transplantation
Transplantation antigens have been found on the cell surface of virtually all tissues of an animal. Differences in these antigens between members of the same species may be a reflection of small chemical chang...
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In vitro susceptibilities of normal human skin fibroblasts to oncoviruses, and the decreased susceptibility to HSV of fibroblasts from untreated Hodgkin's patients
Fibroblast cultures established from the skin of 56 healthy controls and 15 untreated Stages I and II Hodgkin's patients (HD) were studied in their 3rd, 4th and 5th in vitro passage with respect to transformation...
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The structure of junctions between lens fiber cells
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Article
Anaemia in patients with myelomatosis
Twenty-four untreated patients with myelomatosis were studied in order to characterize their anaemia, using standard haematological and ferrokinetic techniques, together with measurements of circulating erythr...
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Chapter
HLA-DR and Renal Transplantation
The serological detection of leukocyte antigens in man began some 20 years ago. Their subsequent recognition as histocompatibility antigens led to immediate interest in the possible application of leukocyte ty...
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Article
Brain Ia antigens have a bone marrow origin
Our results, using radiation-induced bone marrow chimeras, demonstrate that the la antigen found in the brains of such animals is produced by cells having precursors in the bone marrow. These cells are not imm...
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Article
Human liver alcohol dehydrogenase: ADHIndianapolis results from genetic polymorphism at the ADH 2 gene locus
New molecular forms of human liver alcohol dehydrogenase (ADH), collectively designated ADHIndianapolis (ADHInd), were recently discovered in 29% of liver specimens from Black Americans [Bosron, W. F., Li, T.-K.,...
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Article
A monoclonal antibody recognizing HLA-DR2 on malignant and activated cells
A monoclonal antibody, designated NDS15.38, which recognizes a polymorphic determinant of HLA-DR, was produced from a fusion in which mice were immunized with the human B lymphoblastoid cell line GIR2 (HLA type A...
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2’-Fluoro-5-Iodo-l-β-D-Arabinofuranosylcytosine [FIAC]: Synthesis and Mode of Anti-Herpesvirus Activity
l-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-5-iodocytosine [FIAC or 2’-fluoro-5-iodo-ara-C] is a potent and selective new anti-herpes virus drug. The anti-herpes simplex virus type 1 (HSV-1) activity depends, at ...
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Article
Purification and characterization of mouse alcohol dehydrogenase from two inbred strains that differ in total liver enzyme activity
Alcohol dehydrogenase activity in mouse liver homogenate-supernatants is 1.7 times greater in the C57BL/10 strain than in the BALB/c strain, regardless of whether activity is expressed in units per gram liver,...
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Article
Expression of class I histocompatibility antigens on human T-B lymphoblast hybrids
Expression of class I histocompatibility antigens (HLA-A and B) on hybrids of human T and B lymphoblastoid cell lines (LCL) was examined. The T-LCL CEM expressed low levels of HLA-A and B antigens. CEMR and CEMR....
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Evidence for methylation as a regulatory mechanism in HLA-DR x gene expression
We examined the possibility that one mechanism for controlling HLA-DR α gene expression occurs through DNA hypomethylation. We employed the restriction enzyme Hpa II, which recognizes the sequence 5′CCGG3′ but no...
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Article
Genetically determined differences in liver alcohol dehydrogenase activity in male rats
Alcohol dehydrogenase (EC 1.1.1.1) activity was measured in liver extracts from one outbred and three inbred strains of rats. Strain-specific differences in enzyme activity were observed in the adult male rats...
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HLA in Transplantation
Transplantation is associated with a number of iatrogenic complications and therefore it is perhaps not unreasonable for a discussion on HLA in transplantation to be included in the HLA and Disease Symposium. ...
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Article
Purification and characterization of the Danish (skive) variant of mouse liver alcohol dehydrogenase
The partially inbred Danish (Skive) strain of mice exhibits a form of liver alcohol dehydrogenase (ADH) which differs in electrophoretic mobility from that of all other inbred mouse strains thus far examined, ...
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Chapter
DR3 Heterogeneity in American Blacks
The heterogeneity of DR3-associated haplotypes in American Blacks is striking when compared with that in the Caucasoid populations. In American Blacks, only 7.7% of DR3-positive individuals are Dw3. Three DR3-...
