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Chapter
Contribution of 3,4-Dichlorophenylhydroxylamine in Propanil-Induced Hemolytic Anemia
The methemoglobinemia and hemolytic anemia observed in experimental animals given aniline has been shown to be mediated by its N-oxidation metabolite, phenylhydroxylamine (Harrison, J.H. et al., 1987; Harrison...
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Chapter
Arylamine-Induced Hemolytic Anemia: Electron Spin Resonance Spectrometry Studies
A variety of arylamine derivatives (e.g. dapsone, primaquine) are known to produce hemolytic anemia in man and experimental animals. Extensive studies in the 1950’s and 60’s established that hemolytic drugs in...