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Article
Erratum to: Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway
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Article
Colquhounia root tablet in the treatment of idiopathic membranous nephropathy with subnephrotic proteinuria
Idiopathic membranous nephropathy (IMN) is the most frequent global cause of nephrotic syndrome in non-diabetic people. In clinical practice, An effective and mild treatment for IMN patients with subnephrotic ...
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Article
Open AccessAchievable information rate optimization in C-band optical fiber communication system
Optical fiber communication networks play an important role in the global telecommunication network. However, nonlinear effects in the optical fiber and transceiver noise greatly limit the performance of fiber...
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Article
Open AccessAlamandine alleviated heart failure and fibrosis in myocardial infarction mice
Alamandine (Ala) is the newest identified peptide of the renin-angiotensin system and has protective effect on myocyte hypertrophy. However, it is still unclear whether Ala can alleviate heart failure (HF). Th...
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Article
Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts
The extent of myocardial fibrosis is closely related to the prognosis of diabetic cardiomyopathy (DCM). Low-intensity pulsed ultrasound (LIPUS) has been reported to have multiple biological effects. However, t...
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Article
Open AccessThe balance between AIM2-associated inflammation and autophagy: the role of CHMP2A in brain injury after cardiac arrest
Activation of the absent in melanoma 2 (AIM2) inflammasome and impaired autophagosome clearance in neurons contribute significantly to cardiac arrest and return of spontaneous circulation (CA-ROSC) injury, whi...
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Article
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway
Objective: Cardiac hypertrophy and fibrosis are major pathological manifestations observed in left ventricular remodeling induced by angiotensin II (AngII). Low-intensity pulsed ultrasound (LIPUS) has been rep...
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Article
Open AccessLiquid crystal-amplified optofluidic biosensor for ultra-highly sensitive and stable protein assay
Protein assays show great importance in medical research and disease diagnoses. Liquid crystals (LCs), as a branch of sensitive materials, offer promising applicability in the field of biosensing. Herein, we d...
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Article
Open AccessEfficacy and safety of cinacalcet compared with other treatments for secondary hyperparathyroidism in patients with chronic kidney disease or end-stage renal disease: a meta-analysis
It is controversial for the effect and safety between cinacalcet and other treatments in treating secondary hyperparathyroidism for patients with chronic kidney disease (CKD) or end-stage renal disease (ESRD).
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Article
Region duplication detection based on image segmentation and keypoint contexts
In this paper, a novel region duplication detection method is proposed based on image segmentation and keypoint contexts. The proposed method includes the primary region duplication detection based on keypoint...
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Article
Open AccessDigital nonlinearity compensation in high-capacity optical communication systems considering signal spectral broadening effect
Nyquist-spaced transmission and digital signal processing have proved effective in maximising the spectral efficiency and reach of optical communication systems. In these systems, Kerr nonlinearity determines ...
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Article
Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment
In light of the rapid increase in the number of obesity incidences worldwide, obesity has become an independent risk factor for chronic kidney disease. Obesity-related glomerulopathy (ORG) is characterized by ...
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Article
Novel adjuvant for immunization against tuberculosis: DNA vaccine expressing Mycobacterium tuberculosis antigen 85A and interleukin-15 fusion product elicits strong immune responses in mice
To investigate the potential of interleukin (IL)-15 as a novel adjuvant for Mycobacterium tuberculosis (Mtb) antigen 85A (Ag85A) vaccine.
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Article
Open AccessPrevalence and related factors of depressive symptoms in hemodialysis patients in northern China
To determine the prevalence of depressive symptoms and to explore related factors of depressive symptoms in hemodialysis (HD) patients in northern China.
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Article
Open AccessEgg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells via SKP2/P27 signaling pathway
Schistosomiasis is characterized by egg deposition, granulomatous inflammatory reaction and then subsequent hepatic fibrosis formation. Activated HSCs are regarded as the main effector cells in the progression...
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Article
Open AccessEffect of omega-3 fatty acid supplementation on serum lipids and vascular inflammation in patients with end-stage renal disease: a meta-analysis
Omega-3 fatty acids (O3FAs) are associated with lower cardiovascular disease (CVD) risk in adults. However, this association in patients with end-stage renal disease (ESRD) remains controversial prompting the ...
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Article
Open AccessEgg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells by activation of the STAT3/p53/p21 pathway
Liver fibrosis is a serious disease that is characterized by the excess deposition of extracellular matrix (ECM) components. Activated hepatic stellate cells (HSCs) are a major source of ECM and serve as a key...
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Article
Open AccessEqualization enhanced phase noise in Nyquist-spaced superchannel transmission systems using multi-channel digital back-propagation
Superchannel transmission spaced at the symbol rate, known as Nyquist spacing, has been demonstrated for effectively maximizing the optical communication channel capacity and spectral efficiency. However, the ...
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Article
Open AccessSpectrally Shaped DP-16QAM Super-Channel Transmission with Multi-Channel Digital Back-Propagation
The achievable transmission capacity of conventional optical fibre communication systems is limited by nonlinear distortions due to the Kerr effect and the difficulty in modulating the optical field to effecti...
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Chapter and Conference Paper
Middleware-Based Distributed CTCS-3 Simulation Platform
In recent years, with the rapid development of the high-speed railway, the safety and efficient operations are increasingly higher requirements. Railway accidents are caused by many factors, such as human fact...
