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  1. Article

    Open Access

    Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer

    TRIM62 (tripartite motif containing 62) has been found to act as a tumor suppressor of several cancers. However, its precise biological role and related mechanism remain unknown in cervical cancer (CC).

    Tian-Yu Liu, Jian Chen, Chun-Liang Shang in Journal of Experimental & Clinical Cancer … (2016)

  2. No Access

    Article

    BTB domain-containing 7 predicts low recurrence and suppresses tumor progression by deactivating Notch1 signaling in breast cancer

    BTB domain-containing 7 (BTBD7) has been found to regulate epithelial tissue remodeling and branched organ formation and has been reported to modulate the biological behavior of several cancers. However, its r...

    Jian Chen, Yuan-Hui Lai, Shiyin Ooi, Yan Song in Breast Cancer Research and Treatment (2020)

  3. Article

    Open Access

    Development and validation of a survival nomogram for patients with Siewert type II/III adenocarcinoma of the esophagogastric junction based on real-world data

    The clinical staging systems for adenocarcinoma of the esophagogastric junction (AEG) are controversial. We aimed to propose a prognostic nomogram based on real-world data for predicting survival of Siewert ty...

    Jian Chen, Yu-Jian **a, Tian-Yu Liu, Yuan-Hui Lai, Ji-Shang Yu in BMC Cancer (2021)

  4. No Access

    Article

    CPEB3 suppresses gastric cancer progression by inhibiting ADAR1-mediated RNA editing via localizing ADAR1 mRNA to P bodies

    Deciphering the crosstalk between RNA-binding proteins and corresponding RNAs will provide a better understanding of gastric cancer (GC) progression. The comprehensive bioinformatics study identified cytoplasm...

    Jian Chen, Lu Li, Tian-Yu Liu, Hua-Feng Fu, Yuan-Hui Lai, **ong Lei, Jun-Fa Xu in Oncogene (2022)