-
Chapter
Genetic adjuvants for DNA immunization
The injection of naked plasmid DNA expression vectors into animal muscle or skin has been shown to be an effective means to stimulate cellular and humoral immunity against the expressed protein [36]. However, ...
-
Chapter
DNA vaccines with rapid intracellular degradation are more effective for inducing CTL
DNA vaccines have several advantages over conventional vaccines, such as ease of construction, low expense for mass production, high temperature stability, and ability to induce a full spectrum of exceptionall...
-
Chapter and Conference Paper
Studies of HIV Infection and the Development of Epstein-Barr Virus-Related B Cell Lymphomas Following Transfer of Human Lymphocytes to Mice With Severe Combined Immunodeficiency
Mice with severe combined immunodeficiency (C.B-17 scid, hereafter SCID) accept xenografts of adult human peripheral blood leukocytes (PBL). The transplanted human PBL expand in number and survive for at least th...
-
Chapter
Switching the Isotype of Monoclonal Antibodies
Isotype switch variant selection is an important adjunct to monoclonal antibody technology. Through the production of hybridomas, we can now harness the specificity of the humoral immune response to generate v...
-
Article
Genetic map** of the BGL idiotypic marker within theIgh-V region