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Article
Open AccessActivation of the transcription factor, nuclear factor kappa-B, during the estrous cycle and early pregnancy in the pig
Establishment and maintenance of pregnancy in the pig involves intricate communication between the develo** conceptuses and the maternal endometrium. This process occurs during trophoblast elongation which i...
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Protocol
Methods for Studying Interferon Tau Stimulated Genes
Interferon (IFN)τ, a Type I IFN produced by the conceptus trophectoderm, is the pregnancy recognition signal in ruminants that prevents development of the endometrial luteolytic mechanism. In addition, IFNτ ac...
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Protocol
Sheep Uterine Gland Knockout (UGKO) Model
Endometrial gland development is a postnatal event in the ovine uterus that can be inhibited epigenetically by chronic exposure of ewe lambs to a synthetic progestin after birth. The uterus of neonatally proge...
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Article
Open AccessTrophoblast biology: Forum introduction
In mammals, a carefully orchestrated dialogue between the mother and conceptus (embryo/fetus and associate extraembryonic membranes) is initiated during the peri-implantation period of pregnancy as the trophob...
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Article
Open AccessConceptus signals for establishment and maintenance of pregnancy
Establishment and maintenance of pregnancy results from signaling by the conceptus (embryo/fetus and associated extraembryonic membranes) and requires progesterone produced by the corpus luteum (CL). In most m...
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Article
Open AccessEffects of the estrous cycle, pregnancy and interferon tau on expression of cyclooxygenase two (COX-2) in ovine endometrium
In sheep, the uterus produces luteolytic pulses of prostaglandin F2α (PGF) on Days 15 to 16 of estrous cycle to regress the corpus luteum (CL). These PGF pulses are produced by the endometrial lumenal epithelium ...
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Chapter and Conference Paper
Cytokines and Pregnancy Recognition
Maternal recognition of pregnancy results from signaling between the trophoblast of the conceptus (embryo and associated membranes) and the maternal system (1). These signals ensure maintenance of the structur...