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Article
Open AccessPlasma ALS and Gal-3BP differentiate early from advanced liver fibrosis in MASLD patients
Metabolic dysfunction-associated steatotic liver disease (MASLD) is estimated to affect 30% of the world’s population, and its prevalence is increasing in line with obesity. Liver fibrosis is closely related t...
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Article
Open AccessCorrection: Phase 1b/2 trial of tepotinib in sorafenib pretreated advanced hepatocellular carcinoma with MET overexpression
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Article
Open AccessPhase 1b/2 trial of tepotinib in sorafenib pretreated advanced hepatocellular carcinoma with MET overexpression
This Phase 1b/2 study evaluated tepotinib, a highly selective MET inhibitor, in US/European patients with sorafenib pretreated advanced hepatocellular carcinoma (aHCC) with MET overexpression.
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mTOR and Cancer Therapy: Clinical Development and Novel Prospects
mTOR, a pivotal signal transduction protein involved in multiple cellular functions in tumors at the level of cancer and stroma cells, represents an attractive target for cancer therapy. Rapamycin and several ...