-
Article
Purification and characterization of a thermophilic chitinase produced by Aeromonas sp. DYU-Too7
An extracellular chitinase, produced by Aeromonas sp. DYU-Too7, was purified in the following procedures: ammonium sulfate precipitation, ultrafiltration, chromatographic separation of DEAE-sepharose CL-6B and se...
-
Article
Open AccessActivated protein C ameliorates Bacillus anthracis lethal toxin-induced lethal pathogenesis in rats
Lethal toxin (LT) is a major virulence factor of Bacillus anthracis. Sprague Dawley rats manifest pronounced lung edema and shock after LT treatments, resulting in high mortality. The heart failure that is induce...
-
Article
Open AccessDifferent effects of granulocyte colony-stimulating factor and erythropoietin on erythropoiesis
Red blood cells are the most abundant cells in the blood that deliver oxygen to the whole body. Erythropoietin (EPO), a positive regulator of erythropoiesis, is currently the major treatment for chronic anemia...
-
Article
Open AccessThioacetamide-induced liver damage and thrombocytopenia is associated with induction of antiplatelet autoantibody in mice
Thrombocytopenia is usually associated with liver injury, elevated plasma aspartate aminotransferase and alanine aminotransferase levels, and high antiplatelet immunoglobulin (Ig) titers, although the mechanis...
-
Article
Open AccessSuppressed humoral immunity is associated with dengue nonstructural protein NS1-elicited anti-death receptor antibody fractions in mice
Dengue virus (DENV) infections may cause life-threatening dengue hemorrhagic fever (DHF). Suppressed protective immunity was shown in these patients. Although several hypotheses have been formulated, the mecha...
-
Article
Open AccessPlatelet-derived circulating soluble P-selectin is sufficient to induce hematopoietic stem cell mobilization
Granulocyte colony-stimulating factor (G-CSF)-mediated mobilization of hematopoietic stem cells (HSCs) is a well-established method to prepare HSCs for transplantation nowadays. A sufficient number of HSCs is ...
