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Article
Open AccessDynamic genome evolution in a model fern
The large size and complexity of most fern genomes have hampered efforts to elucidate fundamental aspects of fern biology and land plant evolution through genome-enabled research. Here we present a chromosomal...
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Article
Open AccessPhenotypes and outcomes in middle-aged patients with diabetic foot ulcers: a retrospective cohort study
Although ageing could increase the risk of delayed healing in diabetic foot ulcers (DFUs) patients, data from middle-aged patients remains greatly limited. The purpose of this study was to explore the clinical...
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Article
Open AccessGenetic variation of HvXYN1 associated with endoxylanase activity and TAX content in barley (Hordeum vulgare L.)
Endo-β-1,4-xylanase1 (EA), the key endoxylanase in plants, is involved in the degradation of arabinoxylan during grain germination. In barley (Hordeum vulgare L.), one gene (HvXYN-1) that encode a endo-beta-1,4-x...
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Article
Open AccessOlfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP–PKA pathway
Ectopic expression and functions of odorant receptors (ORs) in the human body have aroused much interest in the past decade. Mouse olfactory receptor 23 (MOR23, olfr16) and its human orthologue, OR10J5, have b...
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Article
Open AccessAdenylyl cyclase 3 haploinsufficiency confers susceptibility to diet-induced obesity and insulin resistance in mice
Adenylyl cyclase 3 (Adcy3), a member of the mammalian adenylyl cyclase family responsible for generating the second messenger cAMP, has long been known to play an essential role in olfactory signal transduction. ...
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Article
Open AccessEarliest tea as evidence for one branch of the Silk Road across the Tibetan Plateau
Phytoliths and biomolecular components extracted from ancient plant remains from Chang’an (**’an, the city where the Silk Road begins) and Ngari (Ali) in western Tibet, China, show that the tea was grown 2100 ...
