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  1. No Access

    Article

    IL-17E, a proinflammatory cytokine, has antitumor efficacy against several tumor types in vivo

    Interleukin-17E (IL-17E) belongs to a novel family of cytokines that possess significant homology to IL-17. IL-17E has potent inflammatory effects in vitro and in vivo. Overexpression of IL-17E in mice results...

    Tania Benatar, Ming Y. Cao, Yoon Lee, Jeff Lightfoot… in Cancer Immunology, Immunotherapy (2010)

  2. No Access

    Article

    Virulizin® induces production of IL-17E to enhance antitumor activity by recruitment of eosinophils into tumors

    Virulizin® has demonstrated strong antitumor efficacy in a variety of human tumor xenograft models including melanoma, pancreatic cancer, breast cancer, ovarian cancer and prostate cancer. Our previous studies ha...

    Tania Benatar, Ming Y. Cao, Yoon Lee, Hui Li… in Cancer Immunology, Immunotherapy (2008)

  3. No Access

    Article

    Virulizin, a novel immunotherapy agent, activates NK cells through induction of IL-12 expression in macrophages

    Virulizin, a novel biological response modifier, has demonstrated significant antitumor efficacy in a variety of human tumor xenograft models including melanoma, pancreatic cancer, breast cancer, ovarian cance...

    Hui Li, Ming Y. Cao, Yoon Lee, Vivian Lee… in Cancer Immunology, Immunotherapy (2005)