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    Book

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    Chapter

    Cell Fusion-Mediated Nuclear Reprogramming of Somatic Cells

    Epigenetic reprogramming of nuclei from differentiated to pluripotent state can be induced by three experimental approaches: nuclear transfer, cell fusion, and transduction of transcription factors. In cell fu...

    Kunio Hirano, Takashi Tada in Nuclear Reprogramming and Stem Cells (2012)

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    Protocol

    Generation of Induced Pluripotent Stem Cells from Human Amnion Cells

    Induced pluripotent stem (iPS) cells have been generated through nuclear reprogramming of somatic cells via retrovirus- or lentivirus-mediated transduction of exogenous reprogramming factors OCT3/4, SOX2, KLF4, a...

    Masashi Toyoda, Shogo Nagata, Hatsune Makino in Human Embryonic and Induced Pluripotent St… (2012)

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    Chapter

    Epilogue

    Recent fascinating developments in the interwoven areas of molecular biology, biochemistry, and biomedicine are starting to provide explanations for many complicated “phenomena,” enabling them to be broken dow...

    Takashi Tada, Justin Ainscough, Shinya Yamanaka in Nuclear Reprogramming and Stem Cells (2012)

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    Article

    Familiarity and Prudence of the Japanese Public with Research into Induced Pluripotent Stem Cells, and Their Desire for its Proper Regulation

    The lack of knowledge of current public attitudes towards basic research into induced pluripotent stem cells (iPSCs) is a serious problem when considering appropriate ways of governance regarding research and ...

    Ryuma Shineha, Masahiro Kawakami, Koji Kawakami in Stem Cell Reviews and Reports (2010)