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    Target chromosomes of inducible deletion by a Cre/inverted loxP system in mouse embryonic stem cells

    Chromosomal deletions are widely involved in serious genetic diseases and in the pathogenesis of cancers. These deletions often generate loss of heterozygosity (LOH) of one of the alleles of a tumor suppressor...

    Masako Tada, Hiroyuki Matsumura, Yuko Kurose, Norio Nakatsuji… in Chromosome Research (2009)