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Article
Frequency and covariates of fear of death during myocardial infarction and its impact on prehospital delay: findings from the multicentre MEDEA Study
Fear of death (FoD) is an exceptionally stressful symptom of ST-elevation myocardial infarction (STEMI), which received little scientific attention in recent years. We aimed to describe the prevalence and fact...
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Article
Diastolic dysfunction in exercise and its role for exercise capacity
Diastolic dysfunction is frequent in elderly subjects and in patients with left ventricular hypertrophy, vascular disease and diabetes mellitus. Patients with diastolic dysfunction demonstrate a reduced exerci...
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Article
Open Access1120 Detection of mechanical ventricular asynchrony by cine-MRI
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Article
Impact of intravascular ultrasound guidance on directional coronary atherectomy
Im Gegensatz zur Koronarangiographie kann mittels intravaskulärem Ultraschall (IVUS) neben dem Lumen auch die Gefäßwandstruktur dargestellt werden. Die direktionale Koronaratherektomie (DCA) führt zu einer Lum...
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Article
Östrogene zur Prävention der koronaren Herzkrankheit?
In den letzten Jahren werden zunehmend Frauen in der Menopause mit Östrogenen behandelt. Dies geschieht nicht nur zur Therapie klimakterisch bedingter Beschwerden oder zur Behandlung der Osteoporose, sondern a...
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Chapter
Ventricular tachyarrhythmias, myocardial ischemia and sudden cardiac death in patients with hypertensive heart disease
Hypertensive heart disease is increasingly considered to be a strong and independent risk factor for sudden cardiac death. Ventricular tachyarrhythmias in these patients are common and mainly the result of ele...
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Chapter
Clinical evidence for the fatal interaction of ventricular tachyarrhythmias, myocardial ischemia and sudden cardiac death
During recent years, experimental data have collected convincing evidence for the fatal interaction of myocardial ischemia, ventricular tachyarrhythmias, and sudden cardiac death. In the clinical setting, data...
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Article
Dopexamine in congestive heart failure: how do the pharmacological activities translate into the clinical situation?
Dopexamine is a newly developed sympathetic catecholamine which combines dopaminergic (DA-1) andβ 2-adrenergic agonist activity with only minorβ 1-adrenergic action...
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Chapter and Conference Paper
Incidence and importance of silent myocardial ischaemia — treatment with gallopamil
In view of the prevalence of coronary heart disease, diagnosing and treating myocardial ischaemia is a major challenge. It has been demonstrated in recent years that some patients with proven coronary heart di...
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Article
Effect of tetrodotoxin, lidocaine, and quinidine on the transient inward current of sheep Purkinje fibres
The effect of tetrodotoxin (TTX), lidocaine, and quinidine on the transient inward current (TI) was studied in voltage-clamped sheep cardiac Purkinje fibres. The TI was induced by elevation of extracellular Ca...
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Chapter and Conference Paper
Prevalence of ventricular arrhythmias during silent myocardial ischemia
Symptomatic ST depression at rest and during exercise, as well as the occurrence of ventricular arrhythmias, are known to be independent risk factors in patients with coronary artery disease (1–4). However, th...
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Chapter and Conference Paper
Calcium Antagonists in Silent Myocardial Ischemia — Preliminary Results with Nisoldipine
The use of calcium channel blockers was shown to be effective in the treatment of symptomatic and, more recently, of asymptomatic myocardial ischemia. In this continuing study we evaluated the efficacy of niso...
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Chapter
Mechanical balloon catheter recanalization combined with intracoronary lysis and PTCA
In 127 patients with acute transmural myocardial infarction combined intra venous (iv) and intracoronary (ic) thrombolysis therapy with streptokinase was started. In still occluded vessels a mechanical recanal...
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Chapter and Conference Paper
Acute and chronic changes of myocardial energetics in the mammalian and human heart
In earlier studies using papillary muscles of the rat left ventricle and highly sensitive thermopiles we demonstrated that the heat liberated per gram of myocardium per unit of developed tension-time integral ...
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Chapter and Conference Paper
Influence of phosphodiesterase inhibition on myocardial energetics in dilative cardiomyopathy
The effects of inhibition of phosphodiesterase by enoximone on left ventricular haemodynamics and myocardial energetics were investigated in 10 patients with idiopathic dilative cardiomyopathy. After intraveno...
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Article
Vulnerability of the right ventricle to cathodal, anodal, and bipolar stimulation at double diastolic threshold strength
The repetitive ventricular response (RVR) to three stimulation techniques (bipolar, cathodal and anodal) was investigated in 35 patients. 26 patients suffered from coronary heart disease and 9 patients from di...
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Chapter
Echocardiographic Studies in Cardiomyopathies
Cardiomyopathies comprise a large and inhomogenous group of myocardial diseases. The term primary cardiomyopathy has been proposed for those cases in which a causal factor could not be found.
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Chapter and Conference Paper
Intracardiac Cardioversion for Ablation of the Atrioventricular Conduction System in Patients with Drug Resistant Atrial Flutter
The technique of intracardiac cardioversion for the ablation of the atrioventricular conduction system was used in three male patients (65, 53 and 57 years of age) with atrial flutter unresponsive to medical m...
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Chapter
Isosorbide Dinitrate: Pharmacokinetics After Intravenous Administration
Isosorbide dinitrate (ISDN) is an important organic nitrate found therapeutically useful in its sublingual and oral forms in various cardiovascular diseases such as angina pectoris (1) and congestive heart fai...
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Chapter and Conference Paper
Methods for Non-Invasive Detection of Ventricular Late Potentials — A Comparative Multicenter Study
To evaluate the methodological problems of the non-invasive registration of delayed depolarizations the results obtained with four different averaging systems in the same 109 patients (pts) (80 with coronary a...