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  1. Article

    Gene therapy progress and prospects cancer: oncolytic viruses

    The past 2 years have seen several major advances in oncolytic virotherapy. Studies on the interaction between viruses, immune responses and tumor microenvironment have provided important insight, while clinic...

    T-C Liu, D Kirn in Gene Therapy (2008)

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    Article

    Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus

    Replication-selective oncolytic adenoviruses hold promise, but novel mechanisms must be identified to maximize intratumoral virus persistence, spread and therapeutic transgene-carrying capacity while maintaini...

    T-C Liu, Y Wang, G Hallden, G Brooks, J Francis, N R Lemoine, D Kirn in Gene Therapy (2005)