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    Article

    Toll-like receptors mediate proliferation and survival of multiple myeloma cells

    Multiple myeloma (MM) is an incurable B-cell malignancy characterized by accumulation of malignant plasma cells in bone marrow (BM) and recurrent or persistent infections. Toll-like receptors (TLRs) are essent...

    J Bohnhorst, T Rasmussen, S H Moen, M Fløttum, L Knudsen, M Børset, T Espevik in Leukemia (2006)

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    CD68+/CD83+/CD1a dendritic cell subsets from patients with multiple myeloma are not infected with human herpesvirus 8

    Recently, a subset of dendritic cells with the phenotype CD68+/CD83+/CD1a, present in patients with multiple myeloma (MM), was reported to be infected with human herpesvirus 8 (HHV-8). Therefore we wished to cla...

    T Rasmussen, IMS Dahl, L Jensen, HE Johnsen in Medical Oncology (2000)

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    Article

    Selective loss of progenitor subsets following clinical CD34+ cell enrichment by magnetic field, magnetic beads or chromatography separation

    In this preclinical evaluation we have compared the efficacy of three clinical CD34+enrichment procedures with respect to purity, yield and recovery, as well as risk of selective loss of CD34+ lineage-specific su...

    HE Johnsen, M Hutchings, E Taaning, T Rasmussen, LM Knudsen in Bone Marrow Transplantation (1999)

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    Article

    Reduced bone marrow stem cell pool and progenitor mobilisation in multiple myeloma after melphalan treatment

    The content of stem cells was analysed in bone marrow samples from 75 multiple myeloma patients. In unstimulated bone marrow the percentage of CD34+cells was significantly reduced in 11 patients previously tre...

    L Meldgaard Knudsen, T Rasmussen, L Jensen, HE Johnsen in Medical Oncology (1999)