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Effect of high-dose isoflavones on cognition, quality of life, androgens, and lipoprotein in post-menopausal women

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  1. Article

    Open Access

    Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53

    The tumor suppressor p53 is mainly involved in the transcriptional regulation of a large number of growth-arrest- and apoptosis-related genes. However, a clear understanding of which factor/s influences the ch...

    A Desantis, T Bruno, V Catena, F De Nicola, F Goeman, S Iezzi… in Cell Death & Disease (2015)

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  2. Article

    Open Access

    HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation

    Che-1/AATF is an RNA polymerase II-binding protein that is involved in the regulation of gene transcription, which undergoes stabilization and accumulation in response to DNA damage. We have previously demonst...

    F De Nicola, V Catena, C Rinaldo, T Bruno, S Iezzi, C Sorino… in Cell Death & Disease (2014)

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  3. Article

    Che-1 activates XIAP expression in response to DNA damage

    X-linked inhibitor of apoptosis protein (XIAP) is a member of the inhibitor of apoptosis proteins family that selectively binds and inhibits caspase-3, -7 and -9. As such, XIAP is an extremely potent suppresso...

    T Bruno, S Iezzi, F De Nicola, M Di Padova, A Desantis… in Cell Death & Differentiation (2008)

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