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    Anorexigenic effects induced by RVD-hemopressin(α) administration

    Hemopressin, VD-hemopressin(α) and RVD-hemopressin(α) are hemoglobin α chain derived-peptides which have been found in mouse brain, and where they modulate cannabinoid (CB) receptor function. The nonapeptide h...

    Claudio Ferrante, Lucia Recinella, Sheila Leone in Pharmacological Reports (2017)

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    Emotional disorders induced by Hemopressin and RVD-hemopressin(α) administration in rats

    The endocannabinoid (eCB) system plays an important role in regulating emotional disorders, and is involved, directly or indirectly, in psychiatric diseases, such as anxiety and depression. Hemopressin, a hemo...

    Sheila Leone, Lucia Recinella, Annalisa Chiavaroli in Pharmacological Reports (2017)

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    Effects of central RVD-hemopressin(α) administration on anxiety, feeding behavior and hypothalamic neuromodulators in the rat

    The endocannabinoid (eCB) system is strongly involved in the regulation of anxiety and feeding behavior. RVD-hemopressin(α) [RVD-hp(α)], a N-terminally extended form of hemopressin, is a negative allosteric mo...

    Lucia Recinella, Annalisa Chiavaroli, Claudio Ferrante in Pharmacological Reports (2018)

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    Novel Fubinaca/Rimonabant hybrids as endocannabinoid system modulators

    The discovery of novel modulators of the cannabinoid system is a current topic in medicinal chemistry. In this paper, we report nine novel carboxamides designed as hybrids of Fubinaca family compounds and Rimo...

    Azzurra Stefanucci, Giorgia Macedonio, Szabolcs Dvorácskó, Csaba Tömböly in Amino Acids (2018)