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  1. Article

    Open Access

    Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples

    Sensitive and specific blood-based assays for the detection of pulmonary and extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses, particularly in children. Here we report a nano...

    Wenshu Zheng, Sylvia M. LaCourse, Bofan Song in Nature Biomedical Engineering (2022)

  2. Article

    Open Access

    Evaluation of a serum-based antigen test for tuberculosis in HIV-exposed infants: a diagnostic accuracy study

    Non-sputum methods are urgently needed to improve tuberculosis diagnosis and treatment monitoring in children. This study evaluated the ability of a serum assay quantifying a species-specific peptide of the Mycob...

    Liyan Mao, Sylvia M. LaCourse, Soyeon Kim, Chang Liu, Bo Ning, Duran Bao in BMC Medicine (2021)